2022 American Athletic Conference Leaders Total Defense - Games vs. FBS Teams With Non-Winning Record Only through 01/09/2023
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Navy | 3 | 170 | 580 | 179 | 750 | 4.19 | 250.0 |
| 2 | Cincinnati | 6 | 606 | 1035 | 422 | 1641 | 3.89 | 273.5 |
| 3 | Tulane | 3 | 429 | 422 | 179 | 851 | 4.75 | 283.7 |
| 4 | Memphis | 6 | 621 | 1301 | 392 | 1922 | 4.90 | 320.3 |
| 5 | Temple | 5 | 1125 | 484 | 340 | 1609 | 4.73 | 321.8 |
| 6 | UCF | 5 | 921 | 796 | 320 | 1717 | 5.37 | 343.4 |
| 7 | Tulsa | 4 | 924 | 730 | 285 | 1654 | 5.80 | 413.5 |
| 8 | Houston | 7 | 1016 | 1888 | 483 | 2904 | 6.01 | 414.9 |
| 9 | East Carolina | 4 | 456 | 1207 | 263 | 1663 | 6.32 | 415.8 |
| 10 | SMU | 4 | 935 | 776 | 325 | 1711 | 5.26 | 427.8 |
| 11 | South Florida | 3 | 765 | 758 | 187 | 1523 | 8.14 | 507.7 |