2021 Big Ten Conference Leaders Long Scrimmage Plays - Games vs. Unranked Teams Only (AP Poll) through 01/10/2022
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| Name | Team | Yr | Pos | G | Yards | Yards | Yards | Yards | Yards | Yards | Yards | Yards | Yards | |
| 1 | Jalen Nailor | Mich St | JR | WR | 7 | 17 | 7 | 5 | 4 | 3 | 3 | 0 | 0 | 0 |
| 1 | Samori Toure | Nebraska | SR | WR | 7 | 17 | 12 | 8 | 4 | 3 | 3 | 1 | 0 | 0 |
| 3 | Braelon Allen | Wisconsin | FR | RB | 10 | 30 | 13 | 9 | 4 | 3 | 2 | 2 | 0 | 0 |
| 3 | Dontay Demus Jr. | Maryland | SR | WR | 5 | 13 | 8 | 5 | 3 | 2 | 2 | 0 | 0 | 0 |
| 3 | TreVeyon Henderson | Ohio State | FR | RB | 9 | 32 | 15 | 10 | 7 | 5 | 2 | 1 | 0 | 0 |
| 3 | Adrian Martinez | Nebraska | JR | QB | 7 | 9 | 4 | 2 | 2 | 2 | 2 | 2 | 0 | 0 |
| 3 | Jayden Reed | Mich St | JR | WR | 10 | 32 | 17 | 6 | 4 | 2 | 2 | 2 | 1 | 0 |
| 3 | Broc Thompson | Purdue | JR | WR | 9 | 11 | 3 | 3 | 2 | 2 | 2 | 2 | 0 | 0 |
| 3 | Kenneth Walker III | Mich St | JR | RB | 10 | 44 | 18 | 7 | 3 | 3 | 2 | 2 | 1 | 1 |
| 10 | Daylen Baldwin | Michigan | SR | WR | 10 | 6 | 3 | 3 | 2 | 2 | 1 | 0 | 0 | 0 |
| 10 | AJ Barner | Indiana | SO | TE | 7 | 4 | 2 | 1 | 1 | 1 | 1 | 1 | 0 | 0 |
| 10 | Ronnie Bell | Michigan | SR | WR | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 |
| 10 | Zavier Betts | Nebraska | FR | WR | 7 | 7 | 5 | 3 | 1 | 1 | 1 | 1 | 1 | 0 |
| 10 | Chase Brown | Illinois | SO | RB | 9 | 34 | 10 | 4 | 1 | 1 | 1 | 1 | 1 | 0 |
| 10 | Stephen Carr | Indiana | SR | RB | 4 | 12 | 4 | 1 | 1 | 1 | 1 | 0 | 0 | 0 |
| 10 | Blake Corum | Michigan | SO | RB | 8 | 21 | 8 | 3 | 2 | 2 | 1 | 0 | 0 | 0 |
| 10 | Danny Davis III | Wisconsin | SR | WR | 9 | 16 | 3 | 2 | 1 | 1 | 1 | 1 | 0 | 0 |
| 10 | Jahan Dotson | Penn State | SR | WR | 8 | 27 | 13 | 10 | 5 | 2 | 1 | 1 | 1 | 0 |
| 10 | Payne Durham | Purdue | JR | TE | 8 | 17 | 3 | 2 | 2 | 2 | 1 | 0 | 0 | 0 |
| 10 | Donovan Edwards | Michigan | FR | RB | 9 | 6 | 3 | 2 | 2 | 2 | 1 | 1 | 0 | 0 |
| 10 | Emeka Egbuka | Ohio State | FR | WR | 9 | 4 | 2 | 1 | 1 | 1 | 1 | 1 | 1 | 0 |
| 10 | Tyler Goodson | Iowa | JR | RB | 12 | 36 | 13 | 7 | 5 | 3 | 1 | 0 | 0 | 0 |
| 10 | Isaac Guerendo | Wisconsin | JR | RB | 2 | 2 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 |
| 10 | Hassan Haskins | Michigan | SR | RB | 10 | 30 | 5 | 2 | 2 | 2 | 1 | 0 | 0 | 0 |
| 10 | A.J. Henning | Michigan | SO | WR | 10 | 6 | 3 | 1 | 1 | 1 | 1 | 1 | 0 | 0 |
| 10 | Evan Hull | N'western | SO | RB | 9 | 29 | 4 | 3 | 1 | 1 | 1 | 1 | 1 | 1 |
| 10 | Rakim Jarrett | Maryland | SO | WR | 9 | 23 | 14 | 5 | 2 | 1 | 1 | 0 | 0 | 0 |
| 10 | Cornelius Johnson | Michigan | JR | WR | 10 | 18 | 10 | 4 | 2 | 2 | 1 | 1 | 1 | 0 |
| 10 | Charlie Jones | Iowa | SR | WR | 12 | 10 | 4 | 3 | 1 | 1 | 1 | 1 | 0 | 0 |
| 10 | Darryl Jones | Maryland | SR | WR | 9 | 7 | 4 | 2 | 1 | 1 | 1 | 1 | 0 | 0 |
| 10 | KeAndre Lambert-Smith | Penn State | SO | WR | 8 | 7 | 4 | 4 | 3 | 2 | 1 | 1 | 1 | 0 |
| 10 | Malick Meiga | Penn State | FR | WR | 3 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 |
| 10 | Chez Mellusi | Wisconsin | JR | RB | 6 | 23 | 4 | 2 | 1 | 1 | 1 | 0 | 0 | 0 |
| 10 | Chris Olave | Ohio State | SR | WR | 9 | 23 | 6 | 6 | 2 | 2 | 1 | 0 | 0 | 0 |
| 10 | Brandon Sanders | Rutgers | SR | WR | 7 | 4 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 |
| 10 | Jaxon Smith-Njigba | Ohio State | SO | WR | 9 | 32 | 15 | 7 | 4 | 2 | 1 | 1 | 0 | 0 |
| 10 | Malik Washington | N'western | JR | WR | 9 | 12 | 7 | 3 | 3 | 1 | 1 | 0 | 0 | 0 |
| 10 | Parker Washington | Penn State | SO | WR | 8 | 16 | 6 | 2 | 2 | 2 | 1 | 0 | 0 | 0 |
| 10 | Miyan Williams | Ohio State | FR | RB | 6 | 12 | 3 | 1 | 1 | 1 | 1 | 1 | 0 | 0 |
| 10 | Jaquez Yant | Nebraska | FR | RB | 4 | 5 | 2 | 2 | 1 | 1 | 1 | 0 | 0 | 0 |