2020 Big 12 Conference Leaders Passes Defended - Games vs. FBS Power 5 Conference Teams Only through 01/11/2021
| Name | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|
| 1 | Oklahoma | 10 | 15 | 44 | 59 | 5.90 |
| 1 | Texas | 9 | 9 | 44 | 53 | 5.89 |
| 3 | Oklahoma State | 10 | 5 | 42 | 47 | 4.70 |
| 4 | TCU | 9 | 6 | 41 | 47 | 5.22 |
| 5 | Kansas State | 9 | 6 | 35 | 41 | 4.56 |
| 6 | Iowa State | 11 | 9 | 34 | 43 | 3.91 |
| 7 | Texas Tech | 9 | 4 | 32 | 36 | 4.00 |
| 8 | West Virginia | 8 | 9 | 31 | 40 | 5.00 |
| 8 | Kansas | 8 | 4 | 31 | 35 | 4.38 |
| 10 | Baylor | 9 | 12 | 24 | 36 | 4.00 |