2018 Big 12 Conference Leaders Passes Defended - Games vs. FBS Power 5 Conference Teams Only through 01/07/2019
| Name | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|
| 1 | Oklahoma | 12 | 3 | 53 | 56 | 4.67 |
| 2 | Texas | 13 | 10 | 46 | 56 | 4.31 |
| 3 | Texas Tech | 10 | 9 | 40 | 49 | 4.90 |
| 4 | TCU | 11 | 10 | 39 | 49 | 4.45 |
| 5 | Iowa State | 11 | 6 | 37 | 43 | 3.91 |
| 6 | West Virginia | 11 | 14 | 34 | 48 | 4.36 |
| 7 | Baylor | 11 | 5 | 31 | 36 | 3.27 |
| 8 | Oklahoma State | 10 | 4 | 26 | 30 | 3.00 |
| 9 | Kansas | 10 | 12 | 24 | 36 | 3.60 |
| 9 | Kansas State | 10 | 11 | 24 | 35 | 3.50 |