2020 Conference USA Leaders Total Defense - Games vs. Conference Teams Only through 01/11/2021
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Florida International | 3 | 674 | 469 | 207 | 1143 | 5.52 | 381.0 |
| 2 | UAB | 5 | 523 | 888 | 326 | 1411 | 4.33 | 282.2 |
| 3 | Charlotte | 4 | 702 | 902 | 262 | 1604 | 6.12 | 401.0 |
| 4 | UTEP | 4 | 712 | 918 | 278 | 1630 | 5.86 | 407.5 |
| 5 | Rice | 5 | 704 | 1004 | 300 | 1708 | 5.69 | 341.6 |
| 6 | Western Kentucky | 7 | 1029 | 1061 | 457 | 2090 | 4.57 | 298.6 |
| 7 | Marshall | 6 | 577 | 1202 | 391 | 1779 | 4.55 | 296.5 |
| 8 | Southern Mississippi | 6 | 1004 | 1206 | 433 | 2210 | 5.10 | 368.3 |
| 9 | Florida Atlantic | 6 | 875 | 1255 | 406 | 2130 | 5.25 | 355.0 |
| 10 | Louisiana Tech | 6 | 1045 | 1272 | 431 | 2317 | 5.38 | 386.2 |
| 11 | Middle Tennessee | 6 | 1325 | 1433 | 442 | 2758 | 6.24 | 459.7 |
| 12 | UTSA | 7 | 1015 | 1530 | 479 | 2545 | 5.31 | 363.6 |
| 13 | North Texas | 7 | 1737 | 1569 | 526 | 3306 | 6.29 | 472.3 |