2025 National Leaders Sacks - Games vs. FBS Power 5 Conference Teams Only through 09/12/2025
| Name | G | Sacks | Sack Yards | Sacks/G | |
|---|---|---|---|---|---|
| 1 | Tennessee | 1 | 5.0 | 39 | 5.00 |
| 1 | Delaware | 1 | 5.0 | 30 | 5.00 |
| 3 | Connecticut | 1 | 4.0 | 44 | 4.00 |
| 3 | Western Michigan | 1 | 4.0 | 36 | 4.00 |
| 3 | Duke | 1 | 4.0 | 29 | 4.00 |
| 3 | Boston College | 1 | 4.0 | 28 | 4.00 |
| 3 | Utah | 1 | 4.0 | 28 | 4.00 |
| 3 | Auburn | 1 | 4.0 | 19 | 4.00 |
| 3 | Kansas | 1 | 4.0 | 13 | 4.00 |
| 10 | Kansas State | 2 | 6.0 | 49 | 3.00 |
| 10 | Miami (OH) | 2 | 6.0 | 49 | 3.00 |
| 10 | Ball State | 2 | 6.0 | 42 | 3.00 |
| 10 | Vanderbilt | 1 | 3.0 | 34 | 3.00 |
| 10 | Tulane | 1 | 3.0 | 30 | 3.00 |
| 10 | BYU | 1 | 3.0 | 28 | 3.00 |
| 10 | Florida State | 1 | 3.0 | 28 | 3.00 |
| 10 | Louisiana Tech | 1 | 3.0 | 27 | 3.00 |
| 10 | Colorado State | 1 | 3.0 | 22 | 3.00 |
| 10 | Ole Miss | 1 | 3.0 | 20 | 3.00 |
| 10 | James Madison | 1 | 3.0 | 18 | 3.00 |
| 10 | Stanford | 1 | 3.0 | 18 | 3.00 |
| 10 | Arizona State | 1 | 3.0 | 15 | 3.00 |
| 10 | Houston | 1 | 3.0 | 15 | 3.00 |
| 10 | Cincinnati | 1 | 3.0 | 10 | 3.00 |
| 10 | Rice | 1 | 3.0 | 6 | 3.00 |
| 26 | Ohio | 2 | 5.0 | 24 | 2.50 |
| 27 | Virginia Tech | 2 | 4.0 | 36 | 2.00 |
| 27 | Iowa State | 2 | 4.0 | 29 | 2.00 |
| 27 | Kennesaw State | 2 | 4.0 | 9 | 2.00 |
| 27 | Missouri | 1 | 2.0 | 26 | 2.00 |
| 27 | LSU | 1 | 2.0 | 22 | 2.00 |
| 27 | Mississippi State | 1 | 2.0 | 21 | 2.00 |
| 27 | Buffalo | 1 | 2.0 | 18 | 2.00 |
| 27 | Jacksonville State | 1 | 2.0 | 17 | 2.00 |
| 27 | Utah State | 1 | 2.0 | 16 | 2.00 |
| 27 | TCU | 1 | 2.0 | 13 | 2.00 |
| 27 | Georgia State | 1 | 2.0 | 12 | 2.00 |
| 27 | FIU | 1 | 2.0 | 11 | 2.00 |
| 27 | South Carolina | 1 | 2.0 | 11 | 2.00 |
| 27 | UNLV | 1 | 2.0 | 10 | 2.00 |
| 27 | Oregon | 1 | 2.0 | 10 | 2.00 |
| 27 | Illinois | 1 | 2.0 | 7 | 2.00 |
| 43 | Hawaii | 2 | 3.0 | 33 | 1.50 |
| 43 | Baylor | 2 | 3.0 | 30 | 1.50 |
| 43 | Fresno State | 2 | 3.0 | 28 | 1.50 |
| 46 | Colorado | 2 | 2.0 | 12 | 1.00 |
| 46 | New Mexico | 2 | 2.0 | 5 | 1.00 |
| 46 | Clemson | 1 | 1.0 | 12 | 1.00 |
| 46 | Troy | 1 | 1.0 | 11 | 1.00 |
| 46 | Arizona | 1 | 1.0 | 8 | 1.00 |
| 46 | SMU | 1 | 1.0 | 8 | 1.00 |
| 46 | Notre Dame | 1 | 1.0 | 7 | 1.00 |
| 46 | San Jose State | 1 | 1.0 | 7 | 1.00 |
| 46 | Wake Forest | 1 | 1.0 | 7 | 1.00 |
| 46 | California | 1 | 1.0 | 6 | 1.00 |
| 46 | Southern Miss | 1 | 1.0 | 6 | 1.00 |
| 46 | Oklahoma | 1 | 1.0 | 5 | 1.00 |
| 46 | Missouri State | 1 | 1.0 | 5 | 1.00 |
| 46 | Central Michigan | 1 | 1.0 | 4 | 1.00 |
| 46 | East Carolina | 1 | 1.0 | 4 | 1.00 |
| 46 | Old Dominion | 1 | 1.0 | 4 | 1.00 |
| 46 | Michigan | 1 | 1.0 | 2 | 1.00 |
| 46 | Nevada | 1 | 1.0 | 2 | 1.00 |
| 46 | Ohio State | 1 | 1.0 | 1 | 1.00 |
| 46 | USF | 1 | 1.0 | 1 | 1.00 |
| 66 | NC State | 2 | 1.0 | 6 | 0.50 |