2025 National Leaders Sacks - Games vs. Ranked Teams Only (AP Poll) through 09/12/2025
| Name | G | Sacks | Sack Yards | Sacks/G | |
|---|---|---|---|---|---|
| 1 | Virginia Tech | 1 | 4.0 | 36 | 4.00 |
| 2 | Ball State | 1 | 5.0 | 33 | 5.00 |
| 3 | Kansas State | 1 | 4.0 | 32 | 4.00 |
| 4 | Duke | 1 | 4.0 | 29 | 4.00 |
| 5 | Florida State | 1 | 3.0 | 28 | 3.00 |
| 6 | Boise State | 1 | 4.0 | 27 | 4.00 |
| 6 | Louisiana Tech | 1 | 3.0 | 27 | 3.00 |
| 8 | Miami (FL) | 1 | 3.0 | 24 | 3.00 |
| 9 | LSU | 1 | 2.0 | 22 | 2.00 |
| 10 | Utah State | 1 | 2.0 | 16 | 2.00 |
| 11 | Baylor | 1 | 1.0 | 14 | 1.00 |
| 12 | Kansas | 1 | 4.0 | 13 | 4.00 |
| 13 | Georgia State | 1 | 2.0 | 12 | 2.00 |
| 13 | Clemson | 1 | 1.0 | 12 | 1.00 |
| 15 | FIU | 1 | 2.0 | 11 | 2.00 |
| 15 | Troy | 1 | 1.0 | 11 | 1.00 |
| 17 | Notre Dame | 1 | 1.0 | 7 | 1.00 |
| 17 | San Jose State | 1 | 1.0 | 7 | 1.00 |
| 19 | New Mexico | 1 | 2.0 | 5 | 2.00 |
| 19 | Oklahoma | 1 | 1.0 | 5 | 1.00 |
| 21 | Old Dominion | 1 | 1.0 | 4 | 1.00 |
| 22 | Florida | 1 | 1.0 | 3 | 1.00 |
| 23 | Michigan | 1 | 1.0 | 2 | 1.00 |
| 23 | Nevada | 1 | 1.0 | 2 | 1.00 |
| 25 | Ohio State | 1 | 1.0 | 1 | 1.00 |