2025 National Leaders Total Defense - Games vs. FBS Power 5 Conference Teams Only through 08/23/2025
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Iowa State | 1 | 110 | 273 | 57 | 383 | 6.72 | 383.0 |
| 2 | Fresno State | 1 | 207 | 176 | 58 | 383 | 6.60 | 383.0 |
| 3 | Hawaii | 1 | 177 | 109 | 73 | 286 | 3.92 | 286.0 |
| 4 | Kansas State | 1 | 130 | 183 | 74 | 313 | 4.23 | 313.0 |