2024 American Athletic Conference Leaders Passes Defended - Games vs. FBS Power 5 Conference Teams Only through 01/04/2025
| Name | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|
| 1 | Memphis | 2 | 2 | 8 | 10 | 5.00 |
| 2 | Charlotte | 2 | 1 | 6 | 7 | 3.50 |
| 2 | Tulane | 3 | 3 | 4 | 7 | 2.33 |
| 4 | UAB | 1 | 1 | 5 | 6 | 6.00 |
| 5 | South Florida | 2 | 1 | 4 | 5 | 2.50 |
| 6 | North Texas | 1 | 1 | 3 | 4 | 4.00 |
| 7 | Florida Atlantic | 1 | 2 | 1 | 3 | 3.00 |
| 7 | UTSA | 1 | 1 | 2 | 3 | 3.00 |
| 7 | Temple | 1 | 0 | 3 | 3 | 3.00 |
| 10 | East Carolina | 1 | 1 | 1 | 2 | 2.00 |
| 10 | Tulsa | 1 | 1 | 1 | 2 | 2.00 |
| 12 | Rice | 1 | 0 | 1 | 1 | 1.00 |
| 12 | Navy | 1 | 0 | 1 | 1 | 1.00 |