2024 Conference USA Leaders Total Defense - Games vs. FBS Power 5 Conference Teams Only through 11/23/2024
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Sam Houston State | 1 | 384 | 170 | 74 | 554 | 7.49 | 554.0 |
| 2 | Florida International | 1 | 234 | 180 | 65 | 414 | 6.37 | 414.0 |
| 3 | New Mexico State | 1 | 209 | 356 | 77 | 565 | 7.34 | 565.0 |
| 4 | Jacksonville State | 1 | 233 | 377 | 71 | 610 | 8.59 | 610.0 |
| 5 | Louisiana Tech | 2 | 384 | 431 | 146 | 815 | 5.58 | 407.5 |
| 6 | Western Kentucky | 2 | 445 | 434 | 132 | 879 | 6.66 | 439.5 |
| 7 | UTEP | 2 | 464 | 503 | 151 | 967 | 6.40 | 483.5 |
| 8 | Middle Tennessee | 2 | 382 | 613 | 129 | 995 | 7.71 | 497.5 |