2022 National Leaders Passes Defended - Games vs. Ranked Teams Only (AP Poll) through 01/09/2023
| Name | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|
| 1 | Oregon State | 5 | 1 | 26 | 27 | 5.40 |
| 2 | Alabama | 5 | 3 | 25 | 28 | 5.60 |
| 3 | TCU | 5 | 5 | 23 | 28 | 5.60 |
| 3 | Tennessee | 6 | 4 | 23 | 27 | 4.50 |
| 5 | Washington State | 6 | 3 | 22 | 25 | 4.17 |
| 5 | Stanford | 7 | 2 | 22 | 24 | 3.43 |
| 7 | Georgia | 7 | 10 | 20 | 30 | 4.29 |
| 8 | USC | 7 | 9 | 19 | 28 | 4.00 |
| 9 | Ohio State | 4 | 4 | 18 | 22 | 5.50 |
| 9 | Arkansas | 4 | 3 | 18 | 21 | 5.25 |
| 11 | Utah | 6 | 7 | 17 | 24 | 4.00 |
| 11 | Florida | 7 | 3 | 17 | 20 | 2.86 |
| 11 | Rutgers | 3 | 1 | 17 | 18 | 6.00 |
| 11 | Arizona | 6 | 1 | 17 | 18 | 3.00 |
| 15 | Oregon | 5 | 7 | 16 | 23 | 4.60 |
| 16 | South Carolina | 4 | 4 | 15 | 19 | 4.75 |
| 16 | Georgia Tech | 4 | 1 | 15 | 16 | 4.00 |
| 18 | Michigan | 3 | 4 | 14 | 18 | 6.00 |
| 18 | Kansas State | 5 | 3 | 14 | 17 | 3.40 |
| 18 | Oklahoma | 4 | 2 | 14 | 16 | 4.00 |
| 18 | LSU | 5 | 2 | 14 | 16 | 3.20 |
| 18 | Missouri | 4 | 1 | 14 | 15 | 3.75 |
| 18 | North Carolina | 4 | 1 | 14 | 15 | 3.75 |
| 24 | California | 6 | 2 | 13 | 15 | 2.50 |
| 24 | Texas A&M | 4 | 1 | 13 | 14 | 3.50 |
| 26 | UCLA | 5 | 5 | 12 | 17 | 3.40 |
| 26 | Arizona State | 5 | 4 | 12 | 16 | 3.20 |
| 26 | Clemson | 4 | 2 | 12 | 14 | 3.50 |
| 26 | Boston College | 3 | 1 | 12 | 13 | 4.33 |
| 30 | Oklahoma State | 3 | 3 | 11 | 14 | 4.67 |
| 30 | Illinois | 2 | 2 | 11 | 13 | 6.50 |
| 30 | Texas | 4 | 2 | 11 | 13 | 3.25 |
| 30 | Auburn | 5 | 2 | 11 | 13 | 2.60 |
| 34 | Colorado | 7 | 3 | 10 | 13 | 1.86 |
| 34 | Indiana | 3 | 2 | 10 | 12 | 4.00 |
| 34 | Mississippi | 4 | 2 | 10 | 12 | 3.00 |
| 34 | Fresno State | 2 | 0 | 10 | 10 | 5.00 |
| 34 | Wake Forest | 2 | 0 | 10 | 10 | 5.00 |
| 39 | Purdue | 3 | 3 | 9 | 12 | 4.00 |
| 39 | Notre Dame | 4 | 3 | 9 | 12 | 3.00 |
| 41 | Louisville | 3 | 4 | 8 | 12 | 4.00 |
| 41 | Miami (Florida) | 3 | 3 | 8 | 11 | 3.67 |
| 41 | Mississippi State | 3 | 2 | 8 | 10 | 3.33 |
| 41 | West Virginia | 4 | 2 | 8 | 10 | 2.50 |
| 41 | Baylor | 3 | 1 | 8 | 9 | 3.00 |
| 41 | Kansas | 3 | 1 | 8 | 9 | 3.00 |
| 47 | Syracuse | 4 | 5 | 7 | 12 | 3.00 |
| 47 | Southern Mississippi | 2 | 3 | 7 | 10 | 5.00 |
| 47 | Kentucky | 4 | 3 | 7 | 10 | 2.50 |
| 47 | Bowling Green | 2 | 1 | 7 | 8 | 4.00 |
| 47 | Kent State | 2 | 1 | 7 | 8 | 4.00 |
| 47 | Northwestern | 2 | 1 | 7 | 8 | 4.00 |
| 47 | Vanderbilt | 4 | 0 | 7 | 7 | 1.75 |
| 54 | Pittsburgh | 2 | 4 | 6 | 10 | 5.00 |
| 54 | Boise State | 3 | 4 | 6 | 10 | 3.33 |
| 54 | Penn State | 3 | 3 | 6 | 9 | 3.00 |
| 54 | Duke | 1 | 2 | 6 | 8 | 8.00 |
| 54 | North Carolina State | 2 | 2 | 6 | 8 | 4.00 |
| 54 | San Diego State | 2 | 2 | 6 | 8 | 4.00 |
| 54 | Arkansas State | 2 | 1 | 6 | 7 | 3.50 |
| 54 | UCF | 2 | 1 | 6 | 7 | 3.50 |
| 54 | Louisiana-Lafayette | 2 | 1 | 6 | 7 | 3.50 |
| 54 | Iowa State | 3 | 0 | 6 | 6 | 2.00 |
| 54 | Maryland | 3 | 0 | 6 | 6 | 2.00 |
| 54 | Washington | 4 | 0 | 6 | 6 | 1.50 |
| 66 | Louisiana-Monroe | 3 | 3 | 5 | 8 | 2.67 |
| 66 | Memphis | 2 | 1 | 5 | 6 | 3.00 |
| 66 | Houston | 1 | 0 | 5 | 5 | 5.00 |
| 66 | South Florida | 1 | 0 | 5 | 5 | 5.00 |
| 66 | Florida State | 2 | 0 | 5 | 5 | 2.50 |
| 71 | Marshall | 2 | 4 | 4 | 8 | 4.00 |
| 71 | Georgia State | 1 | 2 | 4 | 6 | 6.00 |
| 71 | BYU | 2 | 2 | 4 | 6 | 3.00 |
| 71 | UTSA | 2 | 2 | 4 | 6 | 3.00 |
| 71 | Virginia Tech | 1 | 1 | 4 | 5 | 5.00 |
| 71 | Wisconsin | 1 | 1 | 4 | 5 | 5.00 |
| 71 | Iowa | 2 | 1 | 4 | 5 | 2.50 |
| 71 | New Mexico | 2 | 1 | 4 | 5 | 2.50 |
| 71 | Central Michigan | 1 | 0 | 4 | 4 | 4.00 |
| 71 | Louisiana Tech | 1 | 0 | 4 | 4 | 4.00 |
| 71 | Virginia | 1 | 0 | 4 | 4 | 4.00 |
| 71 | SMU | 2 | 0 | 4 | 4 | 2.00 |
| 83 | Connecticut | 2 | 2 | 3 | 5 | 2.50 |
| 83 | Texas State | 1 | 1 | 3 | 4 | 4.00 |
| 83 | Tulsa | 1 | 1 | 3 | 4 | 4.00 |
| 83 | UNLV | 2 | 1 | 3 | 4 | 2.00 |
| 83 | Tulane | 2 | 1 | 3 | 4 | 2.00 |
| 83 | Texas Tech | 3 | 1 | 3 | 4 | 1.33 |
| 83 | Akron | 1 | 0 | 3 | 3 | 3.00 |
| 83 | UAB | 1 | 0 | 3 | 3 | 3.00 |
| 83 | Nebraska | 1 | 0 | 3 | 3 | 3.00 |
| 83 | Nevada | 1 | 0 | 3 | 3 | 3.00 |
| 83 | Toledo | 1 | 0 | 3 | 3 | 3.00 |
| 94 | Minnesota | 1 | 1 | 2 | 3 | 3.00 |
| 94 | San Jose State | 1 | 1 | 2 | 3 | 3.00 |
| 94 | Army | 1 | 1 | 2 | 3 | 3.00 |
| 94 | Utah State | 1 | 1 | 2 | 3 | 3.00 |
| 94 | Michigan State | 4 | 1 | 2 | 3 | 0.75 |
| 94 | Ball State | 1 | 0 | 2 | 2 | 2.00 |
| 94 | Cincinnati | 1 | 0 | 2 | 2 | 2.00 |
| 94 | Massachusetts | 1 | 0 | 2 | 2 | 2.00 |
| 94 | Ohio | 1 | 0 | 2 | 2 | 2.00 |
| 94 | Western Michigan | 1 | 0 | 2 | 2 | 2.00 |
| 104 | Appalachian State | 1 | 1 | 1 | 2 | 2.00 |
| 104 | Charlotte | 1 | 1 | 1 | 2 | 2.00 |
| 104 | Western Kentucky | 1 | 1 | 1 | 2 | 2.00 |
| 104 | Hawai'i | 2 | 1 | 1 | 2 | 1.00 |
| 104 | South Alabama | 2 | 1 | 1 | 2 | 1.00 |
| 104 | Colorado State | 1 | 0 | 1 | 1 | 1.00 |
| 104 | East Carolina | 1 | 0 | 1 | 1 | 1.00 |
| 104 | Wyoming | 1 | 0 | 1 | 1 | 1.00 |
| 112 | Navy | 1 | 1 | 0 | 1 | 1.00 |