2022 FBS Independents Leaders Scoring Defense - Games vs. FBS Power 5 Conference Teams Only through 01/09/2023
| Name | G | TD | FG | 1XP | 2XP | Safety | Points | Points/G | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Massachusetts | 1 | 2 | 2 | 2 | 0 | 0 | 20 | 20.0 |
| 1 | Notre Dame | 9 | 26 | 7 | 23 | 0 | 0 | 200 | 22.2 |
| 1 | Connecticut | 4 | 19 | 6 | 19 | 0 | 0 | 151 | 37.8 |
| 1 | Army | 1 | 6 | 1 | 6 | 0 | 0 | 45 | 45.0 |
| 1 | New Mexico State | 3 | 20 | 3 | 20 | 0 | 0 | 149 | 49.7 |
| 6 | Liberty | 3 | 9 | 5 | 6 | 1 | 1 | 79 | 26.3 |
| 6 | BYU | 4 | 18 | 5 | 14 | 1 | 0 | 139 | 34.8 |