2022 Mid-American Conference Leaders Passes Defended - Games vs. FBS non-Power 5 Conference Teams Only through 01/09/2023
| Name | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|
| 1 | Buffalo | 11 | 12 | 52 | 64 | 5.82 |
| 1 | Eastern Michigan | 11 | 12 | 49 | 61 | 5.55 |
| 1 | Ohio | 11 | 12 | 46 | 58 | 5.27 |
| 4 | Toledo | 12 | 11 | 60 | 71 | 5.92 |
| 5 | Miami (Ohio) | 10 | 8 | 40 | 48 | 4.80 |
| 5 | Western Michigan | 9 | 8 | 35 | 43 | 4.78 |
| 5 | Bowling Green | 10 | 8 | 30 | 38 | 3.80 |
| 8 | Akron | 9 | 6 | 31 | 37 | 4.11 |
| 8 | Northern Illinois | 9 | 6 | 31 | 37 | 4.11 |
| 8 | Kent State | 8 | 6 | 21 | 27 | 3.38 |
| 11 | Ball State | 10 | 5 | 55 | 60 | 6.00 |
| 12 | Central Michigan | 9 | 3 | 40 | 43 | 4.78 |