2022 Mid-American Conference Leaders Total Defense - Games in October Only through 01/09/2023
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Northern Illinois | 4 | 419 | 990 | 255 | 1409 | 5.53 | 352.3 |
| 2 | Bowling Green | 4 | 664 | 705 | 258 | 1369 | 5.31 | 342.3 |
| 3 | Central Michigan | 4 | 530 | 798 | 267 | 1328 | 4.97 | 332.0 |
| 4 | Western Michigan | 4 | 366 | 940 | 278 | 1306 | 4.70 | 326.5 |
| 5 | Buffalo | 4 | 652 | 748 | 282 | 1400 | 4.96 | 350.0 |
| 6 | Kent State | 4 | 700 | 1147 | 290 | 1847 | 6.37 | 461.8 |
| 7 | Ohio | 4 | 749 | 1175 | 304 | 1924 | 6.33 | 481.0 |
| 8 | Akron | 5 | 834 | 1209 | 312 | 2043 | 6.55 | 408.6 |
| 9 | Ball State | 4 | 817 | 730 | 320 | 1547 | 4.83 | 386.8 |
| 10 | Eastern Michigan | 5 | 796 | 834 | 329 | 1630 | 4.95 | 326.0 |
| 11 | Miami (Ohio) | 5 | 636 | 1082 | 369 | 1718 | 4.66 | 343.6 |
| 12 | Toledo | 5 | 674 | 1042 | 380 | 1716 | 4.52 | 343.2 |