2022 Big Ten Conference Leaders Total Defense - Games vs. Ranked Teams Only (AP Poll) through 01/09/2023
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Northwestern | 2 | 427 | 216 | 139 | 643 | 4.63 | 321.5 |
| 2 | Iowa | 2 | 238 | 449 | 128 | 687 | 5.37 | 343.5 |
| 3 | Illinois | 2 | 284 | 482 | 141 | 766 | 5.43 | 383.0 |
| 4 | Nebraska | 1 | 264 | 148 | 69 | 412 | 5.97 | 412.0 |
| 5 | Maryland | 3 | 652 | 625 | 212 | 1277 | 6.02 | 425.7 |
| 6 | Rutgers | 3 | 771 | 511 | 212 | 1282 | 6.05 | 427.3 |
| 7 | Michigan | 3 | 517 | 731 | 198 | 1248 | 6.30 | 416.0 |
| 8 | Penn State | 3 | 700 | 706 | 222 | 1406 | 6.33 | 468.7 |
| 9 | Michigan State | 4 | 779 | 1191 | 298 | 1970 | 6.61 | 492.5 |
| 10 | Indiana | 3 | 684 | 930 | 233 | 1614 | 6.93 | 538.0 |
| 11 | Purdue | 3 | 543 | 838 | 197 | 1381 | 7.01 | 460.3 |
| 12 | Minnesota | 1 | 175 | 304 | 67 | 479 | 7.15 | 479.0 |
| 13 | Ohio State | 4 | 574 | 1224 | 248 | 1798 | 7.25 | 449.5 |
| 14 | Wisconsin | 1 | 258 | 281 | 70 | 539 | 7.70 | 539.0 |