2022 Big Ten Conference Leaders Interceptions - Games vs. Ranked Teams Only (AP Poll) through 01/09/2023
| Name | Team | Yr | Pos | G | Int. | Yards | TD | Int./G | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Chris Jefferson | Purdue | SR | S | 1 | 1 | 72 | 1 | 1.00 |
| 2 | Justin Walley | Minnesota | SO | DB | 1 | 1 | 37 | 0 | 1.00 |
| 3 | Charles Brantley | Mich St | SO | DB | 3 | 1 | 32 | 1 | 0.33 |
| 4 | Ji'Ayir Brown | Penn State | SR | S | 3 | 1 | 22 | 0 | 0.33 |
| 5 | Matthew Bailey | Illinois | FR | DB | 2 | 1 | 17 | 0 | 0.50 |
| 6 | JT Tuimoloau | Ohio State | SO | DE | 4 | 2 | 16 | 1 | 0.50 |
| 7 | Avery Young | Rutgers | SR | DB | 3 | 1 | 15 | 0 | 0.33 |
| 7 | Steele Chambers | Ohio State | SR | LB | 4 | 1 | 15 | 0 | 0.25 |
| 9 | Makari Paige | Michigan | JR | DB | 3 | 1 | 8 | 0 | 0.33 |
| 9 | Mike Sainristil | Michigan | SR | DB | 3 | 1 | 8 | 0 | 0.33 |
| 11 | Zach Harrison | Ohio State | SR | DE | 4 | 1 | 2 | 0 | 0.25 |