2022 American Athletic Conference Leaders Interceptions - Games vs. FBS non-Power 5 Conference Teams Only through 01/09/2023
| Name | G | Int. | Yards | TD | Int./G | |
|---|---|---|---|---|---|---|
| 1 | Memphis | 11 | 13 | 223 | 2 | 1.18 |
| 1 | Temple | 9 | 6 | 136 | 2 | 0.67 |
| 3 | East Carolina | 11 | 9 | 109 | 1 | 0.82 |
| 3 | Cincinnati | 9 | 6 | 33 | 1 | 0.67 |
| 5 | Tulane | 11 | 10 | 40 | 0 | 0.91 |
| 5 | SMU | 10 | 9 | 112 | 0 | 0.90 |
| 5 | Navy | 11 | 8 | 57 | 0 | 0.73 |
| 5 | UCF | 10 | 5 | 34 | 0 | 0.50 |
| 5 | Tulsa | 10 | 5 | 28 | 0 | 0.50 |
| 5 | Houston | 11 | 5 | 107 | 0 | 0.45 |
| 5 | South Florida | 9 | 3 | 12 | 0 | 0.33 |