2022 American Athletic Conference Leaders Interceptions - Games vs. FBS Power 5 Conference Teams Only through 01/09/2023
| Name | G | Int. | Yards | TD | Int./G | |
|---|---|---|---|---|---|---|
| 1 | Cincinnati | 3 | 4 | 71 | 0 | 1.33 |
| 2 | Houston | 2 | 3 | 115 | 1 | 1.50 |
| 3 | South Florida | 2 | 2 | 37 | 0 | 1.00 |
| 4 | East Carolina | 1 | 1 | 34 | 0 | 1.00 |
| 4 | Memphis | 1 | 1 | 0 | 0 | 1.00 |
| 4 | Tulane | 2 | 1 | 0 | 0 | 0.50 |