2022 American Athletic Conference Leaders Scoring Defense - Games in August/September Only through 01/09/2023
| Name | G | TD | FG | 1XP | 2XP | Safety | Points | Points/G | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | University of Central Florida | 4 | 6 | 4 | 6 | 0 | 0 | 54 | 13.5 |
| 1 | Tulane University | 5 | 8 | 5 | 8 | 0 | 0 | 71 | 14.2 |
| 1 | Temple University | 4 | 6 | 6 | 6 | 0 | 0 | 60 | 15.0 |
| 1 | East Carolina University | 4 | 9 | 4 | 9 | 0 | 0 | 75 | 18.8 |
| 1 | University of Cincinnati | 4 | 10 | 4 | 10 | 0 | 0 | 82 | 20.5 |
| 1 | U.S. Naval Academy | 3 | 8 | 5 | 8 | 0 | 0 | 71 | 23.7 |
| 1 | Southern Methodist University | 4 | 12 | 6 | 12 | 0 | 0 | 102 | 25.5 |
| 1 | The University of Tulsa | 4 | 16 | 5 | 16 | 0 | 0 | 127 | 31.8 |
| 1 | University of South Florida | 4 | 18 | 5 | 17 | 0 | 1 | 142 | 35.5 |
| 10 | University of Memphis | 4 | 17 | 3 | 15 | 1 | 0 | 128 | 32.0 |
| 10 | University of Houston | 5 | 21 | 8 | 18 | 1 | 0 | 170 | 34.0 |