2022 American Athletic Conference Leaders Rushing Defense - Games vs. Ranked Teams Only (AP Poll) through 01/09/2023
| Name | G | Att | Yards | Avg. | TD | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Houston | 1 | 28 | 84 | 3.00 | 0 | 28.00 | 84.00 |
| 2 | UCF | 2 | 58 | 409 | 7.05 | 3 | 29.00 | 204.50 |
| 3 | East Carolina | 1 | 32 | 41 | 1.28 | 1 | 32.00 | 41.00 |
| 4 | Navy | 1 | 34 | 66 | 1.94 | 1 | 34.00 | 66.00 |
| 5 | Tulane | 2 | 74 | 318 | 4.30 | 1 | 37.00 | 159.00 |
| 6 | Memphis | 2 | 75 | 283 | 3.77 | 5 | 37.50 | 141.50 |
| 7 | SMU | 2 | 77 | 501 | 6.51 | 8 | 38.50 | 250.50 |
| 8 | Cincinnati | 1 | 48 | 221 | 4.60 | 2 | 48.00 | 221.00 |
| 9 | South Florida | 1 | 51 | 235 | 4.61 | 4 | 51.00 | 235.00 |
| 10 | Tulsa | 1 | 53 | 357 | 6.74 | 1 | 53.00 | 357.00 |