2022 American Athletic Conference Leaders Scoring Defense - Games vs. Conference Teams Only through 01/09/2023
| Name | G | TD | FG | 1XP | 2XP | Safety | Points | Points/G | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | University of Cincinnati | 8 | 20 | 7 | 17 | 0 | 2 | 162 | 20.3 |
| 2 | U.S. Naval Academy | 8 | 24 | 14 | 22 | 1 | 0 | 210 | 26.3 |
| 3 | University of Memphis | 8 | 28 | 6 | 23 | 2 | 0 | 213 | 26.6 |
| 4 | University of Central Florida | 9 | 30 | 12 | 25 | 3 | 0 | 247 | 27.4 |
| 5 | Tulane University | 9 | 28 | 8 | 27 | 0 | 0 | 219 | 24.3 |
| 6 | East Carolina University | 8 | 30 | 12 | 28 | 2 | 0 | 248 | 31.0 |
| 6 | University of Houston | 8 | 34 | 9 | 28 | 0 | 0 | 259 | 32.4 |
| 8 | The University of Tulsa | 8 | 31 | 17 | 29 | 1 | 1 | 270 | 33.8 |
| 9 | Southern Methodist University | 8 | 41 | 9 | 35 | 2 | 1 | 314 | 39.3 |
| 10 | Temple University | 8 | 38 | 8 | 37 | 1 | 0 | 291 | 36.4 |
| 11 | University of South Florida | 8 | 46 | 10 | 44 | 1 | 0 | 352 | 44.0 |