2022 American Athletic Conference Leaders Rushing Defense - From Opponent's 21 To 39 Yard Line through 01/09/2023
| Name | G | Att | Yards | Avg. | TD | Long | 1st | 10+ | 20+ | |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Cincinnati | 13 | 192 | 540 | 2.81 | 0 | 28 | 36 | 13 | 3 |
| 2 | Memphis | 13 | 152 | 507 | 3.34 | 0 | 29 | 36 | 18 | 3 |
| 3 | Navy | 12 | 95 | 230 | 2.42 | 0 | 30 | 13 | 7 | 2 |
| 3 | East Carolina | 13 | 136 | 523 | 3.85 | 0 | 30 | 34 | 18 | 3 |
| 5 | Houston | 13 | 128 | 616 | 4.81 | 0 | 49 | 37 | 16 | 10 |
| 6 | Temple | 12 | 143 | 712 | 4.98 | 0 | 61 | 37 | 25 | 9 |
| 7 | Tulane | 14 | 194 | 746 | 3.85 | 1 | 67 | 36 | 16 | 3 |
| 8 | UCF | 14 | 131 | 591 | 4.51 | 0 | 70 | 29 | 21 | 7 |
| 8 | Tulsa | 12 | 142 | 929 | 6.54 | 1 | 70 | 37 | 24 | 10 |
| 10 | South Florida | 12 | 122 | 1057 | 8.66 | 5 | 75 | 44 | 31 | 13 |
| 11 | SMU | 13 | 160 | 899 | 5.62 | 2 | 76 | 41 | 28 | 9 |
| 1st: First Downs; 10+: Rush attempts of 10 or more yards; 20+: Rush attempts of 20 or more yards | ||||||||||