2022 American Athletic Conference Leaders Sacks - Games in December/January Only through 01/09/2023
| Name | Team | Yr | Pos | G | Sacks | Sack Yards | Sacks/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Keith Cooper Jr. | Tulane | SO | DL | 2 | 1.5 | 16 | 0.75 |
| 2 | Teylor Jackson | ECU | SO | ILB | 1 | 1.0 | 12 | 1.00 |
| 3 | Patrick Jenkins | Tulane | SO | DL | 2 | 2.0 | 10 | 1.00 |
| 3 | Gerard Stringer | ECU | SR | SAF | 1 | 1.0 | 10 | 1.00 |
| 5 | Shaundre Mims | ECU | SR | DL | 1 | 1.0 | 9 | 1.00 |
| 5 | Cam'Ron Jackson | Memphis | SO | DL | 1 | 1.0 | 9 | 1.00 |
| 5 | Shanon Reid | SMU | SR | LB | 1 | 1.0 | 9 | 1.00 |
| 8 | Ivan Pace Jr. | Cincinnati | SR | LB | 1 | 1.0 | 8 | 1.00 |
| 8 | James Stewart | Memphis | FR | DL | 1 | 1.0 | 8 | 1.00 |
| 10 | Darius Hodges | Tulane | SO | DL | 2 | 1.0 | 7 | 0.50 |
| 11 | Jeremy Lewis | ECU | JR | OLB | 1 | 1.0 | 6 | 1.00 |
| 12 | Mbiti Williams Jr. | Navy | SO | CB | 1 | 0.5 | 5 | 0.50 |
| 12 | Colin Ramos | Navy | SO | LB | 1 | 0.5 | 5 | 0.50 |
| 12 | Nick Anderson | Tulane | SR | LB | 2 | 0.5 | 5 | 0.25 |
| 15 | D'Anthony Jones | Houston | SR | DL | 1 | 1.0 | 4 | 1.00 |
| 15 | Jaylon Allen | Memphis | SR | DL | 1 | 1.0 | 4 | 1.00 |
| 17 | Dorian Williams | Tulane | SR | LB | 2 | 1.0 | 3 | 0.50 |
| 18 | William Whitlow Jr. | Memphis | FR | DL | 1 | 1.0 | 2 | 1.00 |
| 18 | John Marshall | Navy | SR | STR | 1 | 1.0 | 2 | 1.00 |
| 18 | Josh Celiscar | UCF | JR | DE | 2 | 1.0 | 2 | 0.50 |