2022 American Athletic Conference Leaders Passes Defended - Games in October Only through 01/09/2023
| Name | Team | Yr | Pos | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Malik Fleming | ECU | JR | CB | 5 | 2 | 4 | 6 | 1.20 |
| 1 | Elias Larry | Navy | SO | CB | 5 | 2 | 2 | 4 | 0.80 |
| 1 | Larry Brooks | Tulane | SR | S | 3 | 2 | 1 | 3 | 1.00 |
| 4 | Art Green | Houston | SR | DB | 3 | 1 | 3 | 4 | 1.33 |
| 4 | Jarius Monroe | Tulane | JR | DB | 3 | 1 | 3 | 4 | 1.33 |
| 4 | Ja'Von Hicks | Cincinnati | SR | S | 4 | 1 | 3 | 4 | 1.00 |
| 4 | Jalen McMurray | Temple | FR | CB | 4 | 1 | 3 | 4 | 1.00 |
| 4 | Dashaun Peele | Navy | SO | CB | 1 | 1 | 2 | 3 | 3.00 |
| 4 | Quindell Johnson | Memphis | SR | DB | 3 | 1 | 2 | 3 | 1.00 |
| 4 | Divaad Wilson | UCF | SR | DB | 4 | 1 | 2 | 3 | 0.75 |
| 4 | Xavier Cullens | Memphis | SR | LB | 4 | 1 | 2 | 3 | 0.75 |
| 4 | Aamaris Brown | S Florida | FR | DB | 4 | 1 | 2 | 3 | 0.75 |
| 4 | Jaise Oliver | Tulsa | JR | S | 4 | 1 | 2 | 3 | 0.75 |
| 4 | Nicholas Straw | Navy | SR | RDR | 5 | 1 | 2 | 3 | 0.60 |
| 4 | Jayce Rogers | Houston | SR | DB | 3 | 1 | 1 | 2 | 0.67 |
| 4 | Isaac Slade-Matautia | SMU | SR | LB | 3 | 1 | 1 | 2 | 0.67 |
| 4 | Arquon Bush | Cincinnati | SR | CB | 4 | 1 | 1 | 2 | 0.50 |
| 4 | Jireh Wilson | ECU | JR | SAF | 5 | 1 | 1 | 2 | 0.40 |
| 4 | Macon Clark | Tulane | SR | S | 3 | 1 | 0 | 1 | 0.33 |
| 4 | Deshawn Pace | Cincinnati | JR | LB | 4 | 1 | 0 | 1 | 0.25 |
| 4 | Tyler Murray | Memphis | SR | LB | 4 | 1 | 0 | 1 | 0.25 |
| 4 | Cincir Evans | Memphis | SR | LB | 4 | 1 | 0 | 1 | 0.25 |
| 4 | Matthew Hill | S Florida | JR | S | 4 | 1 | 0 | 1 | 0.25 |
| 4 | Layton Jordan | Temple | JR | OLB | 4 | 1 | 0 | 1 | 0.25 |
| 4 | Justin Wright | Tulsa | SR | LB | 4 | 1 | 0 | 1 | 0.25 |
| 4 | Gerard Stringer | ECU | SR | SAF | 5 | 1 | 0 | 1 | 0.20 |
| 4 | Julius Wood | ECU | JR | SAF | 5 | 1 | 0 | 1 | 0.20 |
| 4 | Colin Ramos | Navy | SO | LB | 5 | 1 | 0 | 1 | 0.20 |