2022 American Athletic Conference Leaders Long All Purpose Plays - Games vs. Ranked Teams Only (AP Poll) through 01/09/2023
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| Name | Team | Yr | Pos | G | Yards | Yards | Yards | Yards | Yards | Yards | Yards | |
| 1 | Tyjae Spears | Tulane | JR | RB | 2 | 3 | 2 | 1 | 1 | 0 | 0 | 0 |
| 2 | Jake Bailey | SMU | SR | WR | 1 | 2 | 1 | 0 | 0 | 0 | 0 | 0 |
| 2 | Daba Fofana | Navy | SO | FB | 1 | 2 | 1 | 1 | 0 | 0 | 0 | 0 |
| 2 | Lawrence Keys III | Tulane | JR | WR | 2 | 2 | 0 | 0 | 0 | 0 | 0 | 0 |
| 2 | Eddie Lewis | Memphis | SR | WR | 2 | 2 | 1 | 1 | 0 | 0 | 0 | 0 |
| 2 | John Rhys Plumlee | UCF | SR | QB | 2 | 2 | 2 | 1 | 1 | 0 | 0 | 0 |
| 7 | Gerry Bohanon | S Florida | JR | QB | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| 7 | KeSean Carter | Houston | SR | WR | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 |
| 7 | Moochie Dixon | SMU | SO | WR | 2 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| 7 | Jevyon Ducker | Memphis | SO | RB | 2 | 1 | 1 | 1 | 0 | 0 | 0 | 0 |
| 7 | Michel Dukes | S Florida | JR | RB | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| 7 | Dylan Goffney | SMU | SO | WR | 2 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| 7 | Jimmy Horn Jr. | S Florida | SO | WR | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 |
| 7 | Kobe Hudson | UCF | JR | WR | 2 | 1 | 1 | 0 | 0 | 0 | 0 | 0 |
| 7 | Jha'Quan Jackson | Tulane | JR | WR | 2 | 1 | 1 | 1 | 1 | 1 | 1 | 0 |
| 7 | Asa Martin | Memphis | SR | RB | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 |
| 7 | Charles McClelland | Cincinnati | SR | RB | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| 7 | Dea Dea McDougle | Tulane | FR | WR | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| 7 | Ryan O'Keefe | UCF | SR | WR | 2 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| 7 | Michael Pratt | Tulane | JR | QB | 2 | 1 | 1 | 0 | 0 | 0 | 0 | 0 |
| 7 | Dequan Stanley | S Florida | FR | WR | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 |
| 7 | Mark Walker | Navy | SR | WR | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| 7 | Duece Watts | Tulane | SR | WR | 2 | 1 | 1 | 1 | 0 | 0 | 0 | 0 |