2022 Atlantic Coast Conference Leaders Tackles For Loss - Games vs. FBS Power 5 Conference Teams Only through 01/09/2023
| Name | G | TFL | TFL Yards | TFL/G | |
|---|---|---|---|---|---|
| 1 | Clemson | 11 | 91.0 | 383 | 8.27 |
| 2 | Pittsburgh | 11 | 80.0 | 373 | 7.27 |
| 3 | Louisville | 9 | 68.0 | 319 | 7.56 |
| 4 | Florida State | 11 | 72.0 | 309 | 6.55 |
| 5 | North Carolina State | 10 | 76.0 | 281 | 7.60 |
| 5 | Wake Forest | 10 | 62.0 | 281 | 6.20 |
| 7 | Duke | 10 | 46.0 | 268 | 4.60 |
| 8 | Syracuse | 10 | 58.0 | 234 | 5.80 |
| 9 | Georgia Tech | 10 | 60.0 | 225 | 6.00 |
| 10 | Boston College | 9 | 64.0 | 218 | 7.11 |
| 11 | Miami (Florida) | 9 | 64.0 | 213 | 7.11 |
| 12 | Virginia | 8 | 40.0 | 176 | 5.00 |
| 13 | Virginia Tech | 8 | 51.0 | 173 | 6.38 |
| 14 | North Carolina | 10 | 33.0 | 125 | 3.30 |