2022 Atlantic Coast Conference Leaders First Downs - Games vs. FBS Power 5 Conference Teams Only through 01/09/2023
| Name | G | Rush | Pass | Penalty | Total | Total/G | |
|---|---|---|---|---|---|---|---|
| 1 | Pittsburgh | 11 | 114 | 105 | 12 | 231 | 21.0 |
| 2 | Clemson | 11 | 112 | 115 | 25 | 252 | 22.9 |
| 3 | Florida State | 11 | 110 | 127 | 22 | 259 | 23.5 |
| 4 | Duke | 10 | 98 | 94 | 23 | 215 | 21.5 |
| 5 | Wake Forest | 10 | 85 | 153 | 26 | 264 | 26.4 |
| 5 | North Carolina | 10 | 85 | 144 | 17 | 246 | 24.6 |
| 7 | Louisville | 9 | 73 | 83 | 14 | 170 | 18.9 |
| 8 | Syracuse | 10 | 72 | 101 | 21 | 194 | 19.4 |
| 9 | Georgia Tech | 10 | 70 | 88 | 17 | 175 | 17.5 |
| 10 | Miami (Florida) | 9 | 65 | 90 | 19 | 174 | 19.3 |
| 11 | North Carolina State | 10 | 63 | 96 | 27 | 186 | 18.6 |
| 12 | Virginia | 8 | 51 | 67 | 18 | 136 | 17.0 |
| 13 | Boston College | 9 | 47 | 93 | 12 | 152 | 16.9 |
| 14 | Virginia Tech | 8 | 42 | 63 | 20 | 125 | 15.6 |