2022 Atlantic Coast Conference Leaders Passes Defended - Games vs. FBS (I-A) Teams Only through 01/09/2023
| Name | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|
| 1 | Clemson | 13 | 12 | 63 | 75 | 5.77 |
| 2 | Pittsburgh | 12 | 14 | 59 | 73 | 6.08 |
| 3 | Duke | 12 | 10 | 56 | 66 | 5.50 |
| 4 | Wake Forest | 12 | 7 | 57 | 64 | 5.33 |
| 5 | North Carolina State | 12 | 17 | 42 | 59 | 4.92 |
| 6 | North Carolina | 13 | 8 | 46 | 54 | 4.15 |
| 7 | Louisville | 13 | 15 | 38 | 53 | 4.08 |
| 8 | Miami (Florida) | 11 | 11 | 38 | 49 | 4.45 |
| 9 | Florida State | 12 | 8 | 40 | 48 | 4.00 |
| 10 | Virginia Tech | 10 | 4 | 39 | 43 | 4.30 |
| 11 | Georgia Tech | 11 | 8 | 34 | 42 | 3.82 |
| 12 | Boston College | 11 | 5 | 35 | 40 | 3.64 |
| 13 | Virginia | 9 | 5 | 34 | 39 | 4.33 |
| 14 | Syracuse | 12 | 9 | 27 | 36 | 3.00 |