2022 Atlantic Coast Conference Leaders Passes Defended - Games Won Only through 01/09/2023
| Name | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|
| 1 | Clemson | 11 | 11 | 56 | 67 | 6.09 |
| 2 | Pittsburgh | 9 | 13 | 51 | 64 | 7.11 |
| 3 | Duke | 9 | 8 | 47 | 55 | 6.11 |
| 4 | Wake Forest | 8 | 6 | 40 | 46 | 5.75 |
| 5 | Florida State | 10 | 7 | 36 | 43 | 4.30 |
| 6 | North Carolina | 9 | 7 | 34 | 41 | 4.56 |
| 7 | North Carolina State | 8 | 13 | 31 | 44 | 5.50 |
| 7 | Louisville | 8 | 12 | 31 | 43 | 5.38 |
| 9 | Miami (Florida) | 5 | 8 | 19 | 27 | 5.40 |
| 10 | Georgia Tech | 5 | 7 | 17 | 24 | 4.80 |
| 10 | Syracuse | 7 | 5 | 17 | 22 | 3.14 |
| 12 | Virginia | 3 | 1 | 15 | 16 | 5.33 |
| 13 | Boston College | 3 | 4 | 11 | 15 | 5.00 |
| 14 | Virginia Tech | 3 | 1 | 8 | 9 | 3.00 |