2022 Atlantic Coast Conference Leaders Passing Defense - Games in December/January Only through 01/09/2023
| Name | G | Att | Comp | Pct. | Yards | Yards/Att | TD | Int | Rating | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Pittsburgh | 1 | 33 | 22 | 66.7 | 325 | 9.8 | 2 | 4 | 145.15 | 33.0 | 325.0 |
| 2 | Clemson | 2 | 71 | 46 | 64.8 | 524 | 7.4 | 3 | 2 | 135.09 | 35.5 | 262.0 |
| 2 | North Carolina State | 1 | 38 | 20 | 52.6 | 266 | 7.0 | 1 | 2 | 109.59 | 38.0 | 266.0 |
| 4 | Duke | 1 | 35 | 22 | 62.9 | 198 | 5.7 | 0 | 1 | 104.67 | 35.0 | 198.0 |
| 4 | North Carolina | 2 | 65 | 51 | 78.5 | 522 | 8.0 | 3 | 1 | 158.07 | 32.5 | 261.0 |
| 6 | Louisville | 1 | 15 | 7 | 46.7 | 83 | 5.5 | 1 | 0 | 115.15 | 15.0 | 83.0 |
| 6 | Syracuse | 1 | 16 | 11 | 68.8 | 138 | 8.6 | 2 | 0 | 182.45 | 16.0 | 138.0 |
| 6 | Wake Forest | 1 | 48 | 29 | 60.4 | 215 | 4.5 | 1 | 0 | 104.91 | 48.0 | 215.0 |
| 6 | Florida State | 1 | 24 | 14 | 58.3 | 243 | 10.1 | 1 | 0 | 157.13 | 24.0 | 243.0 |