2022 Atlantic Coast Conference Leaders Scoring Defense - Games vs. Ranked Teams Only (AP Poll) through 01/09/2023
| Name | G | TD | FG | 1XP | 2XP | Safety | Points | Points/G | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | North Carolina State | 2 | 5 | 4 | 5 | 0 | 0 | 47 | 23.5 |
| 1 | Louisville | 3 | 10 | 2 | 10 | 0 | 0 | 76 | 25.3 |
| 1 | Duke | 1 | 3 | 2 | 2 | 1 | 0 | 28 | 28.0 |
| 1 | Florida State | 2 | 7 | 3 | 6 | 0 | 0 | 57 | 28.5 |
| 1 | Clemson | 4 | 17 | 2 | 17 | 0 | 0 | 125 | 31.3 |
| 1 | North Carolina | 4 | 18 | 3 | 17 | 1 | 0 | 136 | 34.0 |
| 1 | Pittsburgh | 2 | 9 | 2 | 9 | 0 | 0 | 69 | 34.5 |
| 1 | Georgia Tech | 4 | 17 | 7 | 17 | 0 | 0 | 140 | 35.0 |
| 1 | Wake Forest | 2 | 9 | 3 | 5 | 2 | 0 | 72 | 36.0 |
| 1 | Virginia | 1 | 4 | 3 | 4 | 0 | 0 | 37 | 37.0 |
| 1 | Boston College | 3 | 15 | 5 | 14 | 0 | 0 | 119 | 39.7 |
| 1 | Virginia Tech | 1 | 6 | 1 | 6 | 0 | 0 | 45 | 45.0 |
| 13 | Syracuse | 4 | 15 | 6 | 13 | 1 | 1 | 125 | 31.3 |
| 13 | Miami (Florida) | 3 | 17 | 2 | 17 | 0 | 1 | 127 | 42.3 |