2022 Atlantic Coast Conference Leaders Opponent First Downs - Games vs. Conference Teams Only through 01/09/2023
| Name | G | Rush | Pass | Penalty | Total | Total/G | |
|---|---|---|---|---|---|---|---|
| 1 | Florida State | 8 | 66 | 65 | 14 | 145 | 18.1 |
| 2 | Pittsburgh | 8 | 48 | 71 | 20 | 139 | 17.4 |
| 2 | Virginia Tech | 7 | 61 | 71 | 12 | 144 | 20.6 |
| 4 | Virginia | 7 | 62 | 73 | 16 | 151 | 21.6 |
| 5 | Miami (Florida) | 8 | 76 | 74 | 18 | 168 | 21.0 |
| 6 | Syracuse | 8 | 87 | 77 | 12 | 176 | 22.0 |
| 7 | Louisville | 8 | 76 | 79 | 18 | 173 | 21.6 |
| 8 | Georgia Tech | 8 | 73 | 80 | 21 | 174 | 21.8 |
| 9 | North Carolina State | 8 | 42 | 81 | 20 | 143 | 17.9 |
| 10 | Boston College | 8 | 67 | 82 | 21 | 170 | 21.3 |
| 11 | Clemson | 9 | 56 | 93 | 17 | 166 | 18.4 |
| 12 | Duke | 8 | 61 | 96 | 10 | 167 | 20.9 |
| 13 | Wake Forest | 8 | 65 | 107 | 9 | 181 | 22.6 |
| 14 | North Carolina | 9 | 66 | 110 | 10 | 186 | 20.7 |