2022 Atlantic Coast Conference Leaders Rushing Defense - On 2nd Down through 01/09/2023
| Name | G | Att | Yards | Avg. | TD | Long | 1st | 10+ | 20+ | |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | North Carolina State | 13 | 127 | 434 | 3.42 | 3 | 39 | 26 | 16 | 4 |
| 2 | Virginia Tech | 11 | 128 | 462 | 3.61 | 7 | 29 | 35 | 16 | 2 |
| 2 | Pittsburgh | 13 | 128 | 463 | 3.62 | 7 | 34 | 26 | 17 | 3 |
| 4 | Virginia | 10 | 129 | 410 | 3.18 | 6 | 20 | 36 | 13 | 1 |
| 4 | Miami (Florida) | 12 | 129 | 472 | 3.66 | 5 | 26 | 27 | 15 | 4 |
| 4 | Duke | 13 | 129 | 650 | 5.04 | 0 | 55 | 36 | 22 | 3 |
| 7 | Clemson | 14 | 134 | 598 | 4.46 | 4 | 42 | 38 | 23 | 5 |
| 8 | Boston College | 12 | 143 | 738 | 5.16 | 7 | 60 | 44 | 25 | 11 |
| 9 | Wake Forest | 13 | 149 | 617 | 4.14 | 3 | 43 | 38 | 22 | 5 |
| 10 | Georgia Tech | 12 | 150 | 801 | 5.34 | 7 | 44 | 47 | 25 | 6 |
| 11 | Louisville | 13 | 163 | 528 | 3.24 | 3 | 46 | 48 | 24 | 5 |
| 12 | North Carolina | 14 | 169 | 963 | 5.70 | 9 | 74 | 66 | 23 | 10 |
| 13 | Florida State | 13 | 175 | 693 | 3.96 | 9 | 45 | 51 | 27 | 2 |
| 14 | Syracuse | 13 | 178 | 699 | 3.93 | 5 | 36 | 58 | 22 | 5 |
| 1st: First Downs; 10+: Rush attempts of 10 or more yards; 20+: Rush attempts of 20 or more yards | ||||||||||