2022 Big 12 Conference Leaders First Downs - Games vs. FBS Power 5 Conference Teams Only through 01/09/2023
| Name | G | Rush | Pass | Penalty | Total | Total/G | |
|---|---|---|---|---|---|---|---|
| 1 | Texas Tech | 11 | 116 | 143 | 22 | 281 | 25.5 |
| 2 | TCU | 13 | 124 | 123 | 21 | 268 | 20.6 |
| 3 | Oklahoma | 11 | 134 | 120 | 13 | 267 | 24.3 |
| 4 | Texas | 11 | 106 | 124 | 25 | 255 | 23.2 |
| 5 | West Virginia | 11 | 95 | 117 | 35 | 247 | 22.5 |
| 5 | Kansas State | 12 | 110 | 122 | 15 | 247 | 20.6 |
| 7 | Oklahoma State | 11 | 83 | 129 | 23 | 235 | 21.4 |
| 8 | Kansas | 11 | 78 | 130 | 13 | 221 | 20.1 |
| 9 | Baylor | 9 | 96 | 101 | 13 | 210 | 23.3 |
| 10 | Iowa State | 10 | 58 | 124 | 15 | 197 | 19.7 |