2022 Big 12 Conference Leaders Passes Defended - Games in October Only through 01/09/2023
| Name | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|
| 1 | Baylor | 4 | 7 | 21 | 28 | 7.00 |
| 1 | Oklahoma State | 5 | 6 | 21 | 27 | 5.40 |
| 3 | Texas | 4 | 4 | 20 | 24 | 6.00 |
| 4 | TCU | 5 | 5 | 18 | 23 | 4.60 |
| 5 | Kansas State | 4 | 4 | 15 | 19 | 4.75 |
| 6 | Texas Tech | 4 | 3 | 13 | 16 | 4.00 |
| 7 | Oklahoma | 4 | 6 | 11 | 17 | 4.25 |
| 7 | Kansas | 4 | 5 | 11 | 16 | 4.00 |
| 7 | Iowa State | 4 | 0 | 11 | 11 | 2.75 |
| 10 | West Virginia | 4 | 2 | 8 | 10 | 2.50 |