2022 Big 12 Conference Leaders Interceptions - Games vs. Ranked Teams Only (AP Poll) through 01/09/2023
| Name | G | Int. | Yards | TD | Int./G | |
|---|---|---|---|---|---|---|
| 1 | TCU | 5 | 5 | 95 | 2 | 1.00 |
| 2 | Kansas State | 5 | 3 | 49 | 0 | 0.60 |
| 3 | West Virginia | 4 | 2 | 43 | 1 | 0.50 |
| 4 | Texas Tech | 3 | 1 | 25 | 0 | 0.33 |
| 5 | Oklahoma State | 3 | 3 | 24 | 0 | 1.00 |
| 6 | Oklahoma | 4 | 2 | 20 | 0 | 0.50 |
| 7 | Texas | 4 | 2 | 18 | 0 | 0.50 |
| 8 | Baylor | 3 | 1 | 0 | 0 | 0.33 |
| 8 | Kansas | 3 | 1 | 0 | 0 | 0.33 |