2022 Big 12 Conference Leaders Rushing Defense - Games vs. FBS Power 5 Conference Teams Only through 01/09/2023
| Name | G | Att | Yards | Avg. | TD | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Iowa State | 10 | 359 | 1166 | 3.25 | 8 | 35.90 | 116.60 |
| 2 | Texas | 11 | 384 | 1403 | 3.65 | 12 | 34.91 | 127.55 |
| 3 | Kansas State | 12 | 410 | 1820 | 4.44 | 14 | 34.17 | 151.67 |
| 4 | Baylor | 9 | 332 | 1399 | 4.21 | 21 | 36.89 | 155.44 |
| 5 | West Virginia | 11 | 402 | 1713 | 4.26 | 24 | 36.55 | 155.73 |
| 6 | TCU | 13 | 493 | 2194 | 4.45 | 25 | 37.92 | 168.77 |
| 7 | Texas Tech | 11 | 446 | 2057 | 4.61 | 17 | 40.55 | 187.00 |
| 8 | Oklahoma State | 11 | 424 | 2111 | 4.98 | 21 | 38.55 | 191.91 |
| 9 | Oklahoma | 11 | 461 | 2245 | 4.87 | 28 | 41.91 | 204.09 |
| 10 | Kansas | 11 | 482 | 2452 | 5.09 | 34 | 43.82 | 222.91 |