2022 Big 12 Conference Leaders Rushing Defense - Games vs. Unranked Teams Only (AP Poll) through 01/09/2023
| Name | G | Att | Yards | Avg. | TD | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Iowa State | 9 | 284 | 835 | 2.94 | 6 | 31.56 | 92.78 |
| 2 | Texas | 9 | 338 | 1017 | 3.01 | 10 | 37.56 | 113.00 |
| 3 | Kansas State | 9 | 279 | 1074 | 3.85 | 7 | 31.00 | 119.33 |
| 4 | West Virginia | 8 | 295 | 1313 | 4.45 | 15 | 36.88 | 164.13 |
| 5 | Oklahoma | 9 | 370 | 1336 | 3.61 | 15 | 41.11 | 148.44 |
| 6 | Baylor | 10 | 377 | 1420 | 3.77 | 16 | 37.70 | 142.00 |
| 7 | Texas Tech | 10 | 396 | 1466 | 3.70 | 12 | 39.60 | 146.60 |
| 8 | TCU | 10 | 378 | 1552 | 4.11 | 17 | 37.80 | 155.20 |
| 9 | Oklahoma State | 10 | 382 | 1687 | 4.42 | 16 | 38.20 | 168.70 |
| 10 | Kansas | 10 | 434 | 1918 | 4.42 | 25 | 43.40 | 191.80 |