2022 Big 12 Conference Leaders Long Passing Plays - Games at Home Only through 01/09/2023
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| Name | Team | Yr | Pos | G | Yards | Yards | Yards | Yards | Yards | Yards | Yards | Yards | Yards | |
| 1 | Spencer Sanders | Okla St | SR | QB | 6 | 68 | 27 | 13 | 8 | 0 | 0 | 0 | 0 | 0 |
| 2 | Max Duggan | TCU | SR | QB | 6 | 66 | 26 | 14 | 6 | 4 | 3 | 1 | 0 | 0 |
| 2 | Dillon Gabriel | Oklahoma | JR | QB | 6 | 67 | 26 | 16 | 6 | 4 | 1 | 0 | 0 | 0 |
| 2 | Blake Shapen | Baylor | SO | QB | 6 | 55 | 12 | 7 | 6 | 2 | 2 | 2 | 0 | 0 |
| 5 | Jalon Daniels | Kansas | JR | QB | 5 | 36 | 14 | 8 | 5 | 3 | 1 | 1 | 0 | 0 |
| 6 | Hudson Card | Texas | SO | QB | 7 | 28 | 9 | 5 | 3 | 0 | 0 | 0 | 0 | 0 |
| 6 | JT Daniels | WVU | JR | QB | 5 | 43 | 15 | 7 | 3 | 3 | 1 | 0 | 0 | 0 |
| 6 | Will Howard | Kansas St | JR | QB | 2 | 19 | 9 | 5 | 3 | 1 | 1 | 1 | 1 | 0 |
| 6 | Tyler Shough | Texas Tech | SR | QB | 4 | 31 | 14 | 10 | 3 | 0 | 0 | 0 | 0 | 0 |
| 10 | Jason Bean | Kansas | SR | QB | 6 | 19 | 8 | 4 | 2 | 2 | 0 | 0 | 0 | 0 |
| 10 | Quinn Ewers | Texas | FR | QB | 5 | 38 | 15 | 3 | 2 | 0 | 0 | 0 | 0 | 0 |
| 10 | Donovan Smith | Texas Tech | SO | QB | 7 | 41 | 11 | 6 | 2 | 1 | 0 | 0 | 0 | 0 |
| 13 | Hunter Dekkers | Iowa State | SO | QB | 7 | 76 | 22 | 6 | 1 | 1 | 0 | 0 | 0 | 0 |
| 13 | Kyron Drones | Baylor | FR | QB | 3 | 5 | 2 | 1 | 1 | 1 | 0 | 0 | 0 | 0 |
| 13 | Garrett Greene | WVU | SO | QB | 5 | 13 | 5 | 3 | 1 | 1 | 1 | 1 | 0 | 0 |
| 13 | Gunnar Gundy | Okla St | FR | QB | 3 | 8 | 2 | 1 | 1 | 1 | 1 | 1 | 1 | 0 |
| 13 | Adrian Martinez | Kansas St | SR | QB | 5 | 28 | 9 | 1 | 1 | 1 | 1 | 0 | 0 | 0 |
| 13 | Behren Morton | Texas Tech | FR | QB | 5 | 26 | 7 | 2 | 1 | 1 | 0 | 0 | 0 | 0 |
| 13 | Garret Rangel | Okla St | FR | QB | 2 | 7 | 3 | 2 | 1 | 0 | 0 | 0 | 0 | 0 |