2022 Big 12 Conference Leaders Long Rushing Plays - Games at Home Only through 01/09/2023
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| Name | Team | Yr | Pos | G | Yards | Yards | Yards | Yards | Yards | Yards | Yards | Yards | Yards | |
| 1 | Deuce Vaughn | Kansas St | JR | RB | 7 | 23 | 9 | 4 | 2 | 2 | 2 | 0 | 0 | 0 |
| 2 | Richard Reese | Baylor | FR | RB | 6 | 20 | 6 | 2 | 1 | 1 | 0 | 0 | 0 | 0 |
| 3 | Kendre Miller | TCU | JR | RB | 6 | 19 | 6 | 3 | 3 | 2 | 1 | 0 | 0 | 0 |
| 3 | Devin Neal | Kansas | SO | RB | 6 | 19 | 8 | 5 | 2 | 1 | 1 | 1 | 1 | 0 |
| 5 | Bijan Robinson | Texas | JR | RB | 7 | 18 | 5 | 2 | 2 | 1 | 1 | 1 | 0 | 0 |
| 6 | Eric Gray | Oklahoma | SR | RB | 6 | 17 | 7 | 4 | 1 | 0 | 0 | 0 | 0 | 0 |
| 7 | Dillon Gabriel | Oklahoma | JR | QB | 6 | 13 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 7 | Adrian Martinez | Kansas St | SR | QB | 5 | 13 | 2 | 2 | 2 | 2 | 1 | 0 | 0 | 0 |
| 9 | Tahj Brooks | Texas Tech | JR | RB | 7 | 11 | 3 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| 9 | Tony Mathis Jr. | WVU | SO | RB | 5 | 11 | 3 | 2 | 0 | 0 | 0 | 0 | 0 | 0 |
| 9 | SaRodorick Thompson Jr. | Texas Tech | SR | RB | 7 | 11 | 2 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| 12 | Spencer Sanders | Okla St | SR | QB | 6 | 10 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 13 | Dominic Richardson | Okla St | JR | RB | 6 | 9 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 14 | Emari Demercado | TCU | SR | RB | 6 | 8 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| 14 | DJ Giddens | Kansas St | FR | RB | 7 | 8 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 16 | Jirehl Brock | Iowa State | JR | RB | 6 | 7 | 3 | 2 | 1 | 1 | 1 | 0 | 0 | 0 |
| 16 | Garrett Greene | WVU | SO | QB | 5 | 7 | 2 | 2 | 0 | 0 | 0 | 0 | 0 | 0 |
| 16 | Roschon Johnson | Texas | SR | RB | 7 | 7 | 2 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| 16 | Qualan Jones | Baylor | JR | RB | 6 | 7 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 20 | Max Duggan | TCU | SR | QB | 6 | 6 | 2 | 2 | 1 | 1 | 1 | 0 | 0 | 0 |
| 20 | Ollie Gordon II | Okla St | FR | RB | 7 | 6 | 3 | 1 | 1 | 1 | 0 | 0 | 0 | 0 |
| 22 | Emani Bailey | TCU | JR | RB | 5 | 5 | 3 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| 22 | Jalon Daniels | Kansas | JR | QB | 5 | 5 | 3 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| 22 | CJ Donaldson Jr. | WVU | FR | RB | 3 | 5 | 2 | 2 | 1 | 1 | 1 | 1 | 1 | 0 |
| 22 | Daniel Hishaw Jr. | Kansas | SO | RB | 3 | 5 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 22 | Justin Johnson Jr. | WVU | SO | RB | 6 | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 22 | Cartevious Norton | Iowa State | FR | RB | 5 | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 22 | Deon Silas | Iowa State | SO | RB | 7 | 5 | 3 | 2 | 0 | 0 | 0 | 0 | 0 | 0 |
| 29 | Hunter Dekkers | Iowa State | SO | QB | 7 | 4 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 29 | Marcus Major | Oklahoma | JR | RB | 5 | 4 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 29 | Sevion Morrison | Kansas | SO | RB | 5 | 4 | 2 | 2 | 1 | 0 | 0 | 0 | 0 | 0 |
| 29 | Tyler Shough | Texas Tech | SR | QB | 4 | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 29 | Craig Williams | Baylor | JR | RB | 5 | 4 | 2 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| 34 | Jaylen Anderson | WVU | FR | RB | 4 | 3 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 34 | Jovantae Barnes | Oklahoma | FR | RB | 5 | 3 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 34 | Jason Bean | Kansas | SR | QB | 6 | 3 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 |
| 34 | Hudson Card | Texas | SO | QB | 7 | 3 | 2 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| 34 | Donovan Smith | Texas Tech | SO | QB | 7 | 3 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 39 | Bryson Donnell | Texas Tech | FR | RB | 2 | 2 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| 39 | Josh Fleeks | Baylor | SR | RB | 1 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 39 | Gunnar Gundy | Okla St | FR | QB | 3 | 2 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 39 | Deondre Jackson | Okla St | SO | RB | 5 | 2 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 39 | Sam Jackson | TCU | FR | QB | 3 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 39 | Malik Knowles | Kansas St | SR | WR | 7 | 2 | 2 | 1 | 1 | 1 | 1 | 1 | 0 | 0 |
| 39 | Behren Morton | Texas Tech | FR | QB | 5 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 39 | Jaden Nixon | Okla St | FR | RB | 7 | 2 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 |
| 39 | Jaylin Noel | Iowa State | SO | WR | 7 | 2 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 39 | Blake Shapen | Baylor | SO | QB | 6 | 2 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| 39 | Ky Thomas | Kansas | SO | RB | 4 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 39 | Cam'Ron Valdez | Texas Tech | FR | RB | 1 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |