2022 Conference USA Leaders First Downs - Games vs. Non-Conference Teams Only through 01/09/2023
| Name | G | Rush | Pass | Penalty | Total | Total/G | |
|---|---|---|---|---|---|---|---|
| 1 | Western Kentucky | 6 | 46 | 89 | 15 | 150 | 25.0 |
| 2 | UTSA | 5 | 40 | 79 | 5 | 124 | 24.8 |
| 3 | North Texas | 5 | 52 | 56 | 11 | 119 | 23.8 |
| 3 | Florida Atlantic | 4 | 43 | 42 | 10 | 95 | 23.8 |
| 5 | Charlotte | 4 | 28 | 53 | 12 | 93 | 23.3 |
| 6 | Rice | 5 | 42 | 57 | 11 | 110 | 22.0 |
| 7 | Florida International | 4 | 23 | 51 | 8 | 82 | 20.5 |
| 8 | UAB | 5 | 46 | 39 | 12 | 97 | 19.4 |
| 9 | UTEP | 4 | 26 | 43 | 8 | 77 | 19.3 |
| 10 | Louisiana Tech | 4 | 24 | 39 | 12 | 75 | 18.8 |
| 11 | Middle Tennessee | 5 | 22 | 48 | 12 | 82 | 16.4 |