2022 Conference USA Leaders Opponent Penalties - Games vs. FBS Power 5 Conference Teams Only through 01/09/2023
| Name | G | Pen. | Yards | Pen./G | Yards/G | |
|---|---|---|---|---|---|---|
| 1 | Louisiana Tech | 2 | 16 | 160 | 8.0 | 80.0 |
| 2 | Charlotte | 2 | 18 | 115 | 9.0 | 57.5 |
| 3 | Western Kentucky | 2 | 11 | 110 | 5.5 | 55.0 |
| 4 | UTSA | 1 | 9 | 88 | 9.0 | 88.0 |
| 5 | Rice | 1 | 6 | 60 | 6.0 | 60.0 |
| 6 | UTEP | 1 | 7 | 59 | 7.0 | 59.0 |
| 7 | Florida Atlantic | 1 | 5 | 55 | 5.0 | 55.0 |
| 8 | UAB | 1 | 3 | 39 | 3.0 | 39.0 |
| 9 | Middle Tennessee | 1 | 4 | 15 | 4.0 | 15.0 |