2022 Conference USA Leaders Total Offense - Games vs. FBS Power 5 Conference Teams Only through 01/09/2023
| Name | Team | Yr | Pos | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Chase Cunningham | MTSU | SR | QB | 1 | 29 | 408 | 34 | 437 | 12.85 | 437.0 |
| 2 | Parker McNeil | La Tech | SR | QB | 2 | -5 | 453 | 56 | 448 | 8.00 | 224.0 |
| 3 | N'Kosi Perry | FAU | SR | QB | 1 | 93 | 230 | 43 | 323 | 7.51 | 323.0 |
| 4 | Frank Harris | UTSA | SR | QB | 1 | 38 | 222 | 45 | 260 | 5.78 | 260.0 |
| 5 | Austin Reed | Western Ky | SR | QB | 2 | 28 | 618 | 114 | 646 | 5.67 | 323.0 |
| 6 | Wiley Green | Rice | JR | QB | 1 | 0 | 69 | 13 | 69 | 5.31 | 69.0 |
| 7 | Xavier Williams | Charlotte | FR | QB | 2 | 47 | 192 | 46 | 239 | 5.20 | 119.5 |
| 8 | Dylan Hopkins | UAB | JR | QB | 1 | -6 | 158 | 31 | 152 | 4.90 | 152.0 |
| 9 | Brenden Brady | UTSA | SR | RB | 1 | 70 | 35 | 22 | 105 | 4.77 | 105.0 |
| 10 | Calvin Brownholtz | UTEP | JR | QB | 1 | 0 | 44 | 10 | 44 | 4.40 | 44.0 |
| 11 | Gavin Hardison | UTEP | JR | QB | 1 | -34 | 244 | 49 | 210 | 4.29 | 210.0 |
| 12 | Frank Peasant | MTSU | SO | RB | 1 | 74 | 0 | 19 | 74 | 3.89 | 74.0 |
| 13 | Shadrick Byrd | Charlotte | SO | RB | 2 | 71 | 0 | 20 | 71 | 3.55 | 35.5 |
| 14 | Ronald Awatt | UTEP | SR | RB | 1 | 39 | 0 | 12 | 39 | 3.25 | 39.0 |
| 15 | Zuberi Mobley | FAU | FR | RB | 1 | 28 | 0 | 9 | 28 | 3.11 | 28.0 |
| 16 | TJ McMahon | Rice | JR | QB | 1 | -6 | 65 | 22 | 59 | 2.68 | 59.0 |
| 17 | DeWayne McBride | UAB | JR | RB | 1 | 34 | 0 | 13 | 34 | 2.62 | 34.0 |
| 18 | Larry McCammon III | FAU | JR | RB | 1 | 39 | 0 | 15 | 39 | 2.60 | 39.0 |
| 19 | Ari Broussard | Rice | JR | RB | 1 | 25 | 0 | 15 | 25 | 1.67 | 25.0 |
| 20 | Marquis Crosby | La Tech | FR | RB | 2 | 30 | 0 | 19 | 30 | 1.58 | 15.0 |
Note: To qualify, player must have played in 75% of his team's games and have a minimum of 9.0 plays per game played.