2021 SMU Mustangs Total Defense Split Stats through 01/10/2022
| Split | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G |
|---|---|---|---|---|---|---|---|
| All Games | 12 | 1651 | 3337 | 842 | 4988 | 5.92 | 415.7 |
| at Home | 6 | 805 | 1507 | 417 | 2312 | 5.54 | 385.3 |
| on Road/Neutral Site | 6 | 846 | 1830 | 425 | 2676 | 6.30 | 446.0 |
| in Wins | 8 | 1154 | 1954 | 535 | 3108 | 5.81 | 388.5 |
| in Losses | 4 | 497 | 1383 | 307 | 1880 | 6.12 | 470.0 |
| vs. Conference | 8 | 1105 | 2113 | 555 | 3218 | 5.80 | 402.3 |
| vs. Non-Conference | 4 | 546 | 1224 | 287 | 1770 | 6.17 | 442.5 |
| vs. Ranked (AP) | 2 | 327 | 707 | 147 | 1034 | 7.03 | 517.0 |
| vs. Unranked (AP) | 10 | 1324 | 2630 | 695 | 3954 | 5.69 | 395.4 |
| vs. FBS (I-A) | 11 | 1532 | 3124 | 778 | 4656 | 5.98 | 423.3 |
| vs. FCS (I-AA) | 1 | 119 | 213 | 64 | 332 | 5.19 | 332.0 |
| vs. FBS Winning | 4 | 581 | 1160 | 281 | 1741 | 6.20 | 435.3 |
| vs. FBS Non-Winning | 7 | 951 | 1964 | 497 | 2915 | 5.87 | 416.4 |
| vs. FBS Power 5 | 1 | 170 | 276 | 58 | 446 | 7.69 | 446.0 |
| vs. FBS non-Power 5 | 10 | 1362 | 2848 | 720 | 4210 | 5.85 | 421.0 |
| in August/September | 4 | 546 | 1224 | 287 | 1770 | 6.17 | 442.5 |
| in October | 4 | 561 | 933 | 259 | 1494 | 5.77 | 373.5 |
| in November | 4 | 544 | 1180 | 296 | 1724 | 5.82 | 431.0 |
| in December/January | 0 | 0 | 0 | 0 | 0 | - | - |