2021 Notre Dame Fighting Irish Misc. Defense through 01/10/2022
| Name | Yr | Pos | G | Passes Broken Up | QB Hurries | Fumbles Forced | Kicks/Punts Blocked | |
|---|---|---|---|---|---|---|---|---|
| 1 | Jayson Ademilola | SR | DL | 13 | 2 | 4 | 1 | 0 |
| 2 | Justin Ademilola | JR | DL | 13 | 1 | 4 | 1 | 0 |
| 3 | Bo Bauer | SR | LB | 13 | 5 | 2 | 0 | 0 |
| 4 | JD Bertrand | SO | LB | 13 | 1 | 4 | 1 | 0 |
| 5 | Jordan Botelho | SO | DL | 11 | 0 | 2 | 0 | 0 |
| 6 | TaRiq Bracy | SR | CB | 13 | 2 | 2 | 0 | 0 |
| 7 | DJ Brown | JR | S | 12 | 1 | 0 | 0 | 0 |
| 8 | Howard Cross III | SO | DL | 11 | 0 | 4 | 0 | 0 |
| 9 | Isaiah Foskey | SO | DL | 13 | 1 | 7 | 6 | 0 |
| 10 | Houston Griffith | SR | S | 13 | 0 | 1 | 0 | 0 |
| 11 | Kyle Hamilton | JR | S | 7 | 4 | 0 | 0 | 0 |
| 12 | Cam Hart | SO | CB | 13 | 7 | 0 | 0 | 0 |
| 13 | Kurt Hinish | SR | DL | 11 | 0 | 3 | 0 | 0 |
| 14 | Aidan Keanaaina | FR | DL | 3 | 0 | 1 | 0 | 0 |
| 15 | Jack Kiser | SO | LB | 13 | 5 | 2 | 2 | 0 |
| 16 | Clarence Lewis | SO | CB | 13 | 4 | 0 | 1 | 0 |
| 17 | Rylie Mills | SO | DL | 12 | 0 | 3 | 0 | 0 |
| 18 | Nana Osafo-Mensah | SO | DL | 12 | 0 | 2 | 0 | 0 |
| 19 | Isaiah Pryor | SR | LB | 13 | 1 | 3 | 0 | 0 |
| 20 | Myron Tagovailoa-Amosa | SR | DL | 12 | 1 | 11 | 1 | 1 |
| 21 | Drew White | SR | LB | 12 | 1 | 4 | 0 | 0 |
| Total | 13 | 36 | 59 | 13 | 1 | |||
| Opponents | 13 | 46 | 29 | 7 | 0 |