2021 East Carolina Pirates Total Defense Split Stats through 01/10/2022
| Split | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G |
|---|---|---|---|---|---|---|---|
| All Games | 12 | 1940 | 2782 | 790 | 4722 | 5.98 | 393.5 |
| at Home | 6 | 795 | 1457 | 419 | 2252 | 5.37 | 375.3 |
| on Road/Neutral Site | 6 | 1145 | 1325 | 371 | 2470 | 6.66 | 411.7 |
| in Wins | 7 | 1220 | 1634 | 469 | 2854 | 6.09 | 407.7 |
| in Losses | 5 | 720 | 1148 | 321 | 1868 | 5.82 | 373.6 |
| vs. Conference | 8 | 1270 | 1475 | 488 | 2745 | 5.63 | 343.1 |
| vs. Non-Conference | 4 | 670 | 1307 | 302 | 1977 | 6.55 | 494.3 |
| vs. Ranked (AP) | 2 | 230 | 470 | 129 | 700 | 5.43 | 350.0 |
| vs. Unranked (AP) | 10 | 1710 | 2312 | 661 | 4022 | 6.08 | 402.2 |
| vs. FBS (I-A) | 11 | 1809 | 2392 | 690 | 4201 | 6.09 | 381.9 |
| vs. FCS (I-AA) | 1 | 131 | 390 | 100 | 521 | 5.21 | 521.0 |
| vs. FBS Winning | 6 | 934 | 1581 | 397 | 2515 | 6.34 | 419.2 |
| vs. FBS Non-Winning | 5 | 875 | 811 | 293 | 1686 | 5.75 | 337.2 |
| vs. FBS Power 5 | 1 | 99 | 225 | 63 | 324 | 5.14 | 324.0 |
| vs. FBS non-Power 5 | 10 | 1710 | 2167 | 627 | 3877 | 6.18 | 387.7 |
| in August/September | 4 | 670 | 1307 | 302 | 1977 | 6.55 | 494.3 |
| in October | 4 | 575 | 835 | 260 | 1410 | 5.42 | 352.5 |
| in November | 4 | 695 | 640 | 228 | 1335 | 5.86 | 333.8 |
| in December/January | 0 | 0 | 0 | 0 | 0 | - | - |