2021 National Leaders Sacks - Games in December/January Only through 01/10/2022
| Name | G | Sacks | Sack Yards | Sacks/G | |
|---|---|---|---|---|---|
| 1 | Alabama | 3 | 14.0 | 101 | 4.67 |
| 2 | Baylor | 2 | 12.0 | 90 | 6.00 |
| 3 | Cincinnati | 2 | 10.0 | 62 | 5.00 |
| 4 | Utah State | 2 | 9.0 | 60 | 4.50 |
| 5 | Oklahoma State | 2 | 8.0 | 66 | 4.00 |
| 5 | Georgia | 3 | 8.0 | 64 | 2.67 |
| 5 | Pittsburgh | 2 | 8.0 | 59 | 4.00 |
| 8 | Iowa | 2 | 7.0 | 47 | 3.50 |
| 9 | Central Michigan | 1 | 6.0 | 56 | 6.00 |
| 9 | Wake Forest | 2 | 6.0 | 54 | 3.00 |
| 9 | Wisconsin | 1 | 6.0 | 47 | 6.00 |
| 9 | Western Michigan | 1 | 6.0 | 28 | 6.00 |
| 13 | Michigan State | 1 | 5.0 | 39 | 5.00 |
| 13 | Louisiana-Lafayette | 2 | 5.0 | 36 | 2.50 |
| 13 | Western Kentucky | 2 | 5.0 | 33 | 2.50 |
| 13 | Appalachian State | 2 | 5.0 | 31 | 2.50 |
| 13 | Minnesota | 1 | 5.0 | 30 | 5.00 |
| 13 | Penn State | 1 | 5.0 | 24 | 5.00 |
| 13 | Northern Illinois | 2 | 5.0 | 23 | 2.50 |
| 20 | South Carolina | 1 | 4.0 | 34 | 4.00 |
| 20 | Georgia State | 1 | 4.0 | 32 | 4.00 |
| 20 | Texas Tech | 1 | 4.0 | 31 | 4.00 |
| 20 | San Diego State | 2 | 4.0 | 28 | 2.00 |
| 20 | North Texas | 1 | 4.0 | 26 | 4.00 |
| 20 | Liberty | 1 | 4.0 | 25 | 4.00 |
| 20 | Wyoming | 1 | 4.0 | 25 | 4.00 |
| 20 | UTSA | 2 | 4.0 | 24 | 2.00 |
| 20 | Army | 2 | 4.0 | 23 | 2.00 |
| 20 | Utah | 2 | 4.0 | 21 | 2.00 |
| 20 | Oregon State | 1 | 4.0 | 16 | 4.00 |
| 31 | California | 1 | 3.0 | 37 | 3.00 |
| 31 | Rutgers | 1 | 3.0 | 26 | 3.00 |
| 31 | Kent State | 2 | 3.0 | 23 | 1.50 |
| 31 | Oklahoma | 1 | 3.0 | 16 | 3.00 |
| 31 | USC | 1 | 3.0 | 15 | 3.00 |
| 31 | BYU | 1 | 3.0 | 12 | 3.00 |
| 37 | Arkansas | 1 | 2.0 | 23 | 2.00 |
| 37 | Arizona State | 1 | 2.0 | 22 | 2.00 |
| 37 | Maryland | 1 | 2.0 | 20 | 2.00 |
| 37 | West Virginia | 1 | 2.0 | 20 | 2.00 |
| 37 | Fresno State | 1 | 2.0 | 19 | 2.00 |
| 37 | Toledo | 1 | 2.0 | 19 | 2.00 |
| 37 | LSU | 1 | 2.0 | 18 | 2.00 |
| 37 | North Carolina | 1 | 2.0 | 18 | 2.00 |
| 37 | Houston | 2 | 2.0 | 17 | 1.00 |
| 37 | Purdue | 1 | 2.0 | 16 | 2.00 |
| 37 | Tennessee | 1 | 2.0 | 15 | 2.00 |
| 37 | Florida | 1 | 2.0 | 14 | 2.00 |
| 37 | Eastern Michigan | 1 | 2.0 | 13 | 2.00 |
| 37 | Louisville | 1 | 2.0 | 12 | 2.00 |
| 37 | Marshall | 1 | 2.0 | 12 | 2.00 |
| 37 | UCF | 1 | 2.0 | 3 | 2.00 |
| 37 | Air Force | 1 | 2.0 | 3 | 2.00 |
| 54 | Notre Dame | 1 | 1.0 | 11 | 1.00 |
| 54 | Michigan | 2 | 1.0 | 10 | 0.50 |
| 54 | Coastal Carolina | 1 | 1.0 | 9 | 1.00 |
| 54 | Auburn | 1 | 1.0 | 8 | 1.00 |
| 54 | Oregon | 2 | 1.0 | 8 | 0.50 |
| 54 | Miami (Ohio) | 1 | 1.0 | 7 | 1.00 |
| 54 | Ohio State | 1 | 1.0 | 7 | 1.00 |
| 54 | Old Dominion | 1 | 1.0 | 7 | 1.00 |
| 54 | Tulsa | 1 | 1.0 | 7 | 1.00 |
| 54 | Mississippi State | 1 | 1.0 | 6 | 1.00 |
| 54 | Nevada | 1 | 1.0 | 6 | 1.00 |
| 54 | UAB | 1 | 1.0 | 5 | 1.00 |
| 54 | Clemson | 1 | 1.0 | 5 | 1.00 |
| 54 | Iowa State | 1 | 1.0 | 4 | 1.00 |
| 54 | Middle Tennessee | 1 | 1.0 | 4 | 1.00 |
| 54 | Navy | 1 | 1.0 | 4 | 1.00 |
| 54 | UTEP | 1 | 1.0 | 1 | 1.00 |