2021 National Leaders Interceptions - Games in October Only through 01/10/2022
| Name | Team | Yr | Pos | G | Int. | Yards | TD | Int./G | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Daiyan Henley | Nevada | SR | LB | 5 | 4 | 59 | 1 | 0.80 |
| 1 | Khoury Bethley | Hawai'i | SR | DB | 4 | 3 | 106 | 1 | 0.75 |
| 1 | Coby Bryant | Cincinnati | SR | CB | 5 | 3 | 95 | 1 | 0.60 |
| 1 | Craig Young | Ohio State | SO | SAF | 4 | 2 | 88 | 1 | 0.50 |
| 1 | Jason Taylor II | Okla St | JR | S | 4 | 2 | 85 | 1 | 0.50 |
| 1 | Jordan Battle | Alabama | JR | DB | 4 | 2 | 69 | 1 | 0.50 |
| 1 | Antonio Grier | S Florida | SR | LB | 4 | 2 | 69 | 1 | 0.50 |
| 1 | Nakobe Dean | Georgia | JR | ILB | 4 | 2 | 50 | 1 | 0.50 |
| 1 | Jalen Graham | Purdue | JR | LB | 4 | 2 | 45 | 1 | 0.50 |
| 1 | DQ Thomas | MTSU | SR | LB | 4 | 2 | 43 | 1 | 0.50 |
| 1 | John Petrishen | Pittsburgh | SR | LB | 4 | 2 | 33 | 1 | 0.50 |
| 1 | Steven Jones Jr. | App St | SR | DB | 4 | 2 | 14 | 1 | 0.50 |
| 1 | Tyson Williams | Nevada | SR | DB | 3 | 1 | 49 | 1 | 0.33 |
| 1 | Jon Alexander | Charlotte | SR | DB | 3 | 1 | 41 | 1 | 0.33 |
| 1 | Keyshawn Swanson | Troy | FR | S | 3 | 1 | 33 | 1 | 0.33 |
| 1 | Jahfari Harvey | Miami (Fl) | FR | DL | 3 | 1 | 33 | 1 | 0.33 |
| 1 | Grayson Cash | UAB | JR | S | 4 | 1 | 100 | 1 | 0.25 |
| 1 | Traveon Redd | Wk Forest | SR | DB | 4 | 1 | 83 | 1 | 0.25 |
| 1 | Darius Muasau | Hawai'i | JR | LB | 4 | 1 | 75 | 1 | 0.25 |
| 1 | David Spaulding | S Carolina | SO | DB | 4 | 1 | 74 | 1 | 0.25 |
| 1 | Jarvis Brownlee, Jr. | FSU | FR | DB | 4 | 1 | 70 | 1 | 0.25 |
| 1 | Jaden Dolphin | N Illinois | FR | LB | 4 | 1 | 59 | 1 | 0.25 |
| 1 | Dadrian Taylor | UTSA | SR | OLB | 4 | 1 | 51 | 1 | 0.25 |
| 1 | SirVocea Dennis | Pittsburgh | JR | LB | 4 | 1 | 50 | 1 | 0.25 |
| 1 | Carson Wells | Colorado | JR | OLB | 4 | 1 | 50 | 1 | 0.25 |
| 1 | Corey Mayfield Jr. | UTSA | SR | CB | 4 | 1 | 49 | 1 | 0.25 |
| 1 | Gervarrius Owens | Houston | JR | S | 4 | 1 | 45 | 1 | 0.25 |
| 1 | Trevor Harmanson | UTSA | SR | ILB | 4 | 1 | 40 | 1 | 0.25 |
| 1 | Mekhi Wingo | Missouri | FR | DL | 4 | 1 | 40 | 1 | 0.25 |
| 1 | Dwight McGlothern | LSU | SO | CB | 4 | 1 | 37 | 1 | 0.25 |
| 1 | Anthony Pandy | Arizona | SR | LB | 4 | 1 | 37 | 1 | 0.25 |
| 1 | Malik Fleming | ECU | SO | CB | 4 | 1 | 31 | 1 | 0.25 |
| 1 | Cal Haladay | Mich St | FR | LB | 4 | 1 | 30 | 1 | 0.25 |
| 1 | Jermaine Waller | Va Tech | JR | DB | 4 | 1 | 26 | 1 | 0.25 |
| 1 | Jake Hummel | Iowa State | SR | LB | 4 | 1 | 24 | 1 | 0.25 |
| 1 | Denzel Burke | Ohio State | FR | CB | 4 | 1 | 23 | 1 | 0.25 |
| 1 | Quin Williams | Ga South | JR | OLB | 4 | 1 | 22 | 1 | 0.25 |
| 1 | Tre'Vius Hodges-Tomlinson | TCU | JR | CB | 5 | 1 | 29 | 1 | 0.20 |