2021 Independent Leaders Sacks - Games vs. Ranked Teams Only (AP Poll) through 01/10/2022
| Name | G | Sacks | Sack Yards | Sacks/G | |
|---|---|---|---|---|---|
| 1 | New Mexico State | 4 | 6.0 | 52 | 1.50 |
| 2 | Liberty | 2 | 5.0 | 31 | 2.50 |
| 2 | BYU | 3 | 5.0 | 24 | 1.67 |
| 4 | Notre Dame | 2 | 2.0 | 21 | 1.00 |
| 5 | Connecticut | 2 | 1.0 | 8 | 0.50 |
| 5 | Massachusetts | 1 | 1.0 | 7 | 1.00 |