2021 Independent Leaders Total Defense - Games vs. FBS non-Power 5 Conference Teams Only through 01/10/2022
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Notre Dame | 3 | 383 | 544 | 183 | 927 | 5.07 | 309.0 |
| 2 | BYU | 5 | 714 | 983 | 346 | 1697 | 4.90 | 339.4 |
| 3 | Massachusetts | 7 | 1662 | 1800 | 467 | 3462 | 7.41 | 494.6 |
| 4 | Army | 9 | 919 | 1801 | 508 | 2720 | 5.35 | 302.2 |
| 5 | Connecticut | 7 | 1587 | 1696 | 513 | 3283 | 6.40 | 469.0 |
| 6 | New Mexico State | 9 | 1778 | 2342 | 575 | 4120 | 7.17 | 457.8 |
| 7 | Liberty | 10 | 1363 | 1760 | 690 | 3123 | 4.53 | 312.3 |